Open Access
Review
Issue
Parasite
Volume 18, Number 2, May 2011
Page(s) 115 - 119
DOI https://doi.org/10.1051/parasite/2011182115
Published online 15 May 2011
  1. Berman J.D. & Lee L.S. Activity of 8-aminoquinolines against Leishmania tropica within human macrophages in vitro. American Journal of Tropical Medicine and Hygiene, 1983, 32, 753–759. [Google Scholar]
  2. Beveridge E., Goodwin L.G. & Walls L.P. A new series of leishmanicides. Nature, 1958, 182, 316–317. [CrossRef] [Google Scholar]
  3. Bories C., Cojean S., Huteau F. & Loiseau P.M. Selection and phenotype characterisation of sitamaquine-resistant promastigotes of Leishmania donovani. Biomedicine and Pharmacotherapy, 2008, 62, 164–167. [CrossRef] [Google Scholar]
  4. Coïmbra E.S., Libong D., Cojean S., Saint-Pierre-Chazalet M., Solgadi A., Le Moyec L., Duenas-Romero A.M., Chaminade P. & Loiseau P.M. Mechanism of interaction of sitamaquine with Leishmania donovani. The Journal of Antimicrobial Chemotherapy, 2010, 65, 2548–2555. [CrossRef] [PubMed] [Google Scholar]
  5. Desjeux P. Leishmaniasis: current situation and new perspectives. Comparative Immunology, Microbiology and Infectious Diseases, 2004, 27, 305–318. [CrossRef] [PubMed] [Google Scholar]
  6. Dietze R., Carvalho S.F.G., Valli L.C., Berman J., Brewer T., Milhous W., Sanchez J., Schuster B. & Grogl M. Phase II trial of WR6026, an orally administrated 8-aminoquinoline, in the treatment of visceral leishmaniasis caused by Leishmania chagasi. American Journal of Tropical Medicine and Hygiene, 2001, 65, 685–689. [Google Scholar]
  7. Dueñas-Romero A.M., Loiseau P.M. & Saint-Pierre-Chazalet M. Interaction of sitamaquine with membrane lipids of Leishmania donovani promastigotes. Biochimica et Biophysica Acta, 2007, 1768, 246–252. [CrossRef] [PubMed] [Google Scholar]
  8. Elderfield R.C., Mertel H.E., Mitch R.T., Wempen I.M. & Werble E.J.. Synthesis of primaquine and certain of its analogs. Journal of the American Chemical Society, 1955, 77, 4816–4819. [CrossRef] [Google Scholar]
  9. Garnier T., Brown M.B., Lawrence M.J. & Croft S.L. In vitro and in vivo studies on a topical formulation of sitamaquine dihydrochloride for cutaneous leishmaniasis. Journal of Pharmacy and Pharmacology, 2006, 58, 1043–1054. [CrossRef] [Google Scholar]
  10. Jha T.K., Sundar S., Thakur C.P., Bachmann P., Karbwang J., Fischer C., Voss A. & Berman J. Miltefosine, an oral agent, for the treatment of Indian visceral leishmaniasis. New England Journal of Medicine, 1999, 341, 1795–800. [CrossRef] [Google Scholar]
  11. Jha T.K., Sundar S., Thakur C.P., Felton J.M., Sabin A.J. & Horton J. A phase II dose-ranging study of sitamaquine for treatment of visceral leishmaniasis in India. American Journal of Tropical Medicine and Hygiene, 2005, 73, 1005–1011. [Google Scholar]
  12. Kinnamon K.E., Steck E.A., Loizeaux P.S., Hanson W.L., Chapman W.L. Jr. & Waits V.B. The antileishmanial activity of lepidines. American Journal of Tropical Medicine and Hygiene,, 1978, 27, 751–757. [Google Scholar]
  13. Langreth S.G., Berman J.D., Riordan G.P. & Lee L.S. Finestructure alterations in Leishmania tropica within macrophages exposed to antileishmanial drugs in vitro. Journal of Protozoology, 1983, 30, 555–561. [Google Scholar]
  14. López-Martín C., Pérez-Victoria J.M., Carvalho L., Castanys S. & Gamarro F. Sitamaquine sensitivity in Leishmania species is not mediated by drug accumulation in acidocalcisomes. Antimicrobial Agents and Chemotherapy, 2008, 52, 4030–4036. [CrossRef] [PubMed] [Google Scholar]
  15. Muschiol C., Berger M.R., Schuler B., Scherf H.R., Garzon F.T., Zeller W.J., Unger C., Eibl H.J. & Schmähl D. Alkyl phosphocholines: toxicity and anticancer properties. Lipids, 1987, 22, 930–934. [CrossRef] [PubMed] [Google Scholar]
  16. Sherwood J.A., Gachihi G.S., Muigai R.K., Skillman D.R., Mugo M., Rashid J.R., Wasunna K.M., Were J.B., Kasili S.K. & Mbugua J.M. et al. Phase II efficacy trial of an oral 8-aminoquinoline (WR6026) for treatment of visceral leishmaniasis. Clinical Infectious Diseases, 1994, 19, 1034–1039. [CrossRef] [Google Scholar]
  17. Sindermann H. & Engel J. Development of miltefosine as an oral treatment for leishmaniasis. Transactions of the Royal Society of Tropical Medicine and Hygiene, 2006, 100(Suppl 1), S17–S20. [CrossRef] [PubMed] [Google Scholar]
  18. Soto J., Arana B.A., Toledo J., Rizzo N., Vega J.C., Diaz A., Luz M., Gutierrez P., Arboleda M., Berman J.D., Junge K., Engel J. & Sindermann H. Miltefosine for new world cutaneous leishmaniasis. Clinical Infectious Diseases, 2004, 38, 1266–1272. [CrossRef] [Google Scholar]
  19. Soto J. & Berman J. Treatment of New World cutaneous leishmaniasis with miltefosine. Transactions of the Royal Society of Tropical Medicine and Hygiene, 2006, 100(Suppl 1), S34–S40. [CrossRef] [PubMed] [Google Scholar]
  20. Soto J. & Toledo J.T. Oral miltefosine to treat new world cutaneous leishmaniasis. Lancet Infectious Diseases, 2007, 7, 7. [CrossRef] [Google Scholar]
  21. Sundar S., Jha T.K., Thakur C.P., Engel J., Sindermann H., Fischer C., Junge K., Bryceson A. & Berman J. Oral miltefosine for Indian visceral leishmaniasis. New England Journal of Medicine, 2002, 347, 1739–1746. [CrossRef] [Google Scholar]
  22. Sundar S., Rai M., Chakravarty J., Agarwal D., Agrawal N., Vaillant M., Olliaro P. & Murray H.W. New treatment approach in Indian visceral leishmaniasis: single-dose liposomal amphotericin B followed by short-course oral miltefosine. Clinical Infectious Diseases, 2008, 47, 1000–1006. [CrossRef] [Google Scholar]
  23. Theoharides A.D., Chung H., Velazquez H. Metabolism of a potential 8-aminoquinoline antileishmanial drug in rat liver microsomes. Biochemical Pharmacology, 1985, 34, 181–188. [CrossRef] [PubMed] [Google Scholar]
  24. Theoharides A.D., Kim M.M., Ashmore R.W. & Shipley L.A. Identification and quantification of human urinary metabolites of a candidate 8-aminoquinoline antileishmanial drug WR-6026. Proceedings of American Society of Experimental Biology, 1987, 46, 865. [Google Scholar]
  25. Vercesi A. & Docampo R. Ca2+ transport by digitonin-permeabilized Leishmania donovani. Effects of Ca2+, pentamidine and WR-6026 on mitochondrial membrane potential in situ. Biochemical Journal, 1992, 284, 463–467. [Google Scholar]
  26. Vercesi A., Rodrigues C., Castisti R. & Docampo R. Presence of a Na(+)/H(+) exchanger in acidocalcisomes of Leishmania donovani and their alkalization by anti-leishmanial drugs. FEBS Letters, 2000, 473, 203–206. [CrossRef] [PubMed] [Google Scholar]
  27. Wasunna M.K., Rhashid J.R., Mbui J., Kirigi G., Kinoti D., Lodenyo H., Felton J.M., Sabin A.J. & Horton J. A phase II dose-increasing study of sitamaquine for treatment of visceral leishmaniasis in Kenya. American Journal of Tropical Medicine and Hygiene, 2005, 73, 871–876. [Google Scholar]
  28. World Health Organization. Leishmaniasis Disease Burden. Available from: http://www.who.int/leishmaniasis, 2010. [Google Scholar]
  29. Yeates C. Sitamaquine (GlaxoSmithKline/Walter Reed Army Institute). Current Opinion in Investigational Drugs, 2002, 3, 1446–1452. [Google Scholar]

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