Analysis of changes in the age and sex distribution of GI infections caused by protozoan parasites in Mexico due to the COVID-19 pandemic. A) Incidence of amoebiasis; B) giardiasis; and C) other protozoal infections, with the most affected age group shaded in grey; D) distribution of cases by sex. In figure D, grey represents the average monthly cases of GI infections caused by protozoan parasites in the last three years pre-pandemic (2017–2019), while black represents the number of new cases of gastrointestinal infections caused by protozoan parasites during the COVID-19 pandemic (2020–2022). Statistical analyses were performed using GraphPad Prism version 6.01 for Windows, with significance set at p ≤ 0.05.