Table 5
Test for association of TNF-α gene alleles with morbidity and Hardy–Weinberg equilibrium in patients infected with S. haematobium.
| No. | SNP Name | dbSNP ID number | SNP positions on GRCh38 | Allele associated | IMD Frequency | IMU Frequency | Chi square (χ2) | p-value χ2 | HW p-value |
|---|---|---|---|---|---|---|---|---|---|
| 1 | −1031 T > C | rs1799964 | 31574531 | C | 0.147 | 0.065 | 1.761 | 0.1845 | 0.0173 |
| 2 | −863 C > A | rs1800630 | 31574699 | A | 0.150 | 0.109 | 0.371 | 0.5422 | 0.3106 |
| 3 | −857 C > T | rs1799724 | 31574705 | C | 1.000 | 0.953 | 1.931 | 0.1647 | 0.0972 |
| 4 | −308 G > A | rs1800629 | 31575254 | A | 0.205 | 0.109 | 1.871 | 0.1713 | 0.579 |
| 5 | −113 C > G | rs3093660 | 31575629 | G | 0.130 | 0.029 | 4.486 | 0.0342 | 4.5467E-8 |
| 6 | +87 G > T | rs2228088 | 31575828 | T | 0.087 | 0.043 | 0.952 | 0.3292 | 0.2953 |
| 7 | +489 G > A | rs1800610 | 31576050 | G | 0.978 | 0.971 | 0.051 | 0.8206 | 0.2141 |
NA = not available; GRCh38 = genome reference consortium human build 38; IMU = infected with morbidity undetected on ultrasound; IMD = infected with morbidity detected on ultrasound; SNP = single nucleotide polymorphism; HW = Hardy–Weinberg equilibrium.
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