Table 3
ECP and TNF-α SNP distribution in patients infected with S. haematobium according to the morbidity level revealed by ultrasound (IMD or IMU).
| Genes |
ECP
|
TNF-α
|
|||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Name SNP | +434 G > C | −1031 T > C | −863 C > A | −857 C > T | −308 G > A | −113 C > G | +87 G > T | +489 G > A | |||||||||||||||
| (dbSNP ID number) | (rs2073342) | (rs1799964) | (rs1800630) | (rs1799724) | (rs1800629) | (rs3093660) | (rs2228088) | (rs1800610) | |||||||||||||||
| Genotypes | CC | GG | GC | CC | TT | TC | CC | AA | AC | CC | TT | TC | AA | GG | AG | CC | GG | GG | TT | GT | AA | GG | AG |
| All (%) | 34.2 | 17.1 | 48.7 | 5.2 | 84.5 | 10.3 | 80.6 | 3.2 | 16.2 | 95.2 | 1.6 | 3.2 | 3.1 | 76.6 | 20.3 | 93.2 | 6.8 | 90.4 | 1.4 | 8.2 | 2.7 | 91.8 | 5.5 |
| N = 76 | N = 58 | N = 62 | N = 62 | N = 64 | N = 73 | N = 73 | N = 73 | ||||||||||||||||
| IMD (%) | 34.6 | 23.1 | 42.3 | 5.9 | 76.5 | 17.6 | 70 | 0 | 30 | 100 | 0 | 0 | 4.6 | 63.6 | 31.8 | 84.6 | 15.4 | 84 | 00 | 16 | 00 | 96 | 4 |
| N = 26 | N = 17 | N = 20 | N = 20 | N = 22 | N = 26 | N = 25 | N = 25 | ||||||||||||||||
| IMU (%) | 40.5 | 13.5 | 46 | 6.5 | 93.5 | 0 | 84.4 | 6.2 | 9.4 | 93.8 | 3.1 | 3.1 | 3.1 | 81.3 | 15.6 | 97.3 | 2.7 | 91.9 | 2.7 | 5.4 | 2.7 | 91.9 | 5.4 |
| N = 37 | N = 31 | N = 32 | N = 32 | N = 32 | N = 37 | N = 37 | N = 37 | ||||||||||||||||
| χ2 = 0.98 ; P = 0.71 | χ2 = 5.84 ; p = 0.07 | χ2 = 4.60 ; p = 0.09 | χ2 = 1.3 ; p = 1 | χ2 = 2.16 ; p = 0.37 | Fisher test; p = 0.30 | p = 0.27; χ2 = 2.51 | p = 1 ; χ2 = 0.76 | ||||||||||||||||
IMU = infected with morbidity undetected on ultrasound; IMD = infected with morbidity detected on ultrasound; TNF-α: tumor necrosis factor-alpha; ECP: eosinophil cationic protein, N = sequences number; p = statistical p-value; χ2 = Chi square.
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