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Table 1

List of nucleotide and amino acid polymorphisms in the CestB gene of ex vivo TCBZ-resistant sFg and asF compared to the reference gene of CestB of TCBZ-susceptible F. hepatica.

Accession No Fluke types Ex vivo TCBZ response (Sen/Res) SNP440 SNP643 SNP788 SAAP147 SAAP215 SAAP263
PQ231166 sFg Res A A A K K K
PQ231167 Res A A A K K K
PQ231168 Res A A A K K K
PQ231169 Res A A A K K K
PQ231170 Res A A A K K K
PQ231171 Res A A A K K K
PQ231172 asF Res A A A K K K
PQ231173 Res A A A K K K
PQ231174 Res A A A K K K
PQ231175 Res A A A K K K
MW655750.1 (Reference Gene) Sen G G G R E R

Sen, sensitive; Res, resistance; TCBZ, triclabendazole; sFg, spermic Fasciola gigantica; asF, aspermic Fasciola.

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