Open Access
Review
Table 4
Anti-Cryptosporidium effects of various traditional Chinese medicines in farm animals and host models.
| Therapeutic drug | Experimental model type | Types of infection | Reference | Types of treatment | Efficacy |
|||
|---|---|---|---|---|---|---|---|---|
| Clinical cure |
Parasitological cure |
|||||||
| Degree of diarrhea | Change in weight | Infection intensity | Oocyst shedding | |||||
| Matrine | MDCK cell/BALB/c mice | Experimental | [202] | Therapeutic | NR | + | ||
| Rabbit | Experimental | [125] | Therapeutic | NR | ± | |||
| Oxymatrine | BALB/c mice | Experimental | [98] | Therapeutic | NR | + | ||
| Garlic | Swiss albino mice | Experimental | [65] | Therapeutic/Prophylactic | NR | + | ||
| BALB/c mice | Experimental | [59] | Therapeutic | NR | + | + | ||
| Swiss albino mice | Experimental | [54] | Therapeutic | NR | + | |||
| Halofuginone | HCT-8 cells | Experimental | [164] | Therapeutic | NR | + | ||
| Goat neonates | Experimental | [150] | Prophylactic | + | NR | + | ||
| Neonatal calves | Natural | [175] | Prophylactic | + | − | + | ||
| Pomegranate extract | Neonatal calves | Natural | [183] | Therapeutic | + | + | ||
| Albino mice | Experimental | [4] | Therapeutic | NR | + | |||
| Swiss Albino mice | Experimental | [56] | Therapeutic | NR | − | |||
| Curcumin | BALB/c mice | Experimental | [19] | Therapeutic | NR | + | ||
| HCT-8 cells | Experimental | [155] | Therapeutic | NR | + | |||
| C57BL/6 neonatal mice | Experimental | [152] | Therapeutic | NR | + | |||
Note: “NR” indicates no reported; “+” indicates significant improvement; “−” indicates no significant improvement; and “±” indicates moderate improvement.
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