Efficacy of a topical combination of esafoxolaner, eprinomectin and praziquantel against Amblyomma maculatum infestations in cats

Open Access

Table 1

Efficacy of the investigational veterinary product (IVP) against Amblyomma maculatum infestations 72 h after treatment and subsequent weekly infestations.

Day	3	10	17	24	31	38	45
LS_C (AM untreated control group)	23.3	30.8	27.8	33.7	29.1	28.0	29.0
LS_T (AM IVP treated group)	0.3	0.2	0.3	0.1	1.8	1.1	3.3
% reduction¹	98.7	99.4	98.9	99.7	93.8	96.0	88.6
p-value²	<0.0001	<0.0001	<0.0001	<0.0001	<0.0001	<0.0001	0.0013

The percent reduction was calculated as 100 × [(LS_C − LS_T)/LS_C], where LS_C was the least square arithmetic mean of the live attached tick counts among the untreated control cats and LS_T was the least square arithmetic mean of the live attached tick counts among the IVP treated cats.

p-value: Linear mixed model with treatment as a fixed effect and block as a random effect.

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