Open Access
Review
Table 2
Practical comparison of albendazole and mebendazole for the treatment of alveolar echinococcosis.
Drug | Albendazole | Mebendazole |
---|---|---|
Prodrug | Yes | No |
Pharmaceutical forms | 400 mg tablet | 500 mg tablet |
40 mg/mL oral suspension | 20 mg/mL oral suspension | |
Initial dosage | 10–15 mg/kg/day | 40–50 mg/kg/day |
Plasma concentration targets [13] | Peak of albendazole sulfoxide (4 h after administration): 0.65–3 μMol/L | Peak of mebendazole (4 h after administration): >250 nMol/L |
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