Histological examinations using hematoxylin and eosin (HE) staining to observe the impact of C. sinensis infection on feline bile duct epithelium. A: Intravital collection and morphological observation of C. sinensis. B: HE staining of intrahepatic bile duct tissue from the uninfected group. C, D, and E present the HE staining analysis of intrahepatic bile duct tissues from cats infected with C. sinensis, illustrating epithelial hyperplasia (EH), adenomatous hyperplasia (AH), and carcinoma (CA), respectively. The blue arrows in panels C, D, and E point to the typical bile duct cells under various pathological conditions within the intrahepatic bile duct tissue.