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Table 3

Treatment, follow-up and outcome of AE in patients with solid organ transplantation.

Treatment and outcome
ID Surgical intervention (months from diagnosis) Albendazole Outcome Follow-up (months) Follow-up serology Follow-up imaging
1 Incomplete resection (0 m) No Deceaseda 0
2 Incomplete resection (0 m) 400 mg bid Stabilization 43 Negative at 19 and 42 months b MRI at 32 and 43 months: stabilization
3 No 400 mg bid, increased to 400 mg tid (due to the progression) Progression 49 EgHF ELISA (at 17 and 30 m): positive, titers decreasing PET-CT (at 32 and 49 m): persistence of metabolic activity; progression
AE serology b (at 17 and 30 m): positive, titers increasing MRI at 44 months: progression
Western blot (at 17 and 30 m): positive
4 Incomplete resection (31 m) 400 mg bid, increased to 400/600 mg Deceaseda 31
5 No 400 mg bid Deceased 5
6 Incomplete resectionc (2 months prior diagnosis) 400 mg bid Stabilization 20 Serologyb titers decreasing at 18 and 20 months Chest CT-scan at 6 and 12 months: no new lesion
7 No 400 mg bid Stabilization 48 Eg IHA and ELISAb at 3, 6, 18, 24, 30, 36 and 48 months: decreasing titers (rebound of IHA at 30 m, then decrease) MRI at 18 and 48 months: stabilization
8 Complete resection (14 m) 400 mg bid, decreased to 200 mg bid (supra-therapeutic concentration) Regression 42 EgHF ELISA (0 and 4 m): decreasing titers MRI (9 m): no lesion
Em2+ ELISA (0, 4, 6 m): decreasing titers; negative at 42 m PET-CT : 1 month: residual metabolic activity; 13 and 42 m : no metabolic activity
Eg IHA (0, 4 and 6 m): neg, neg, pos
Western blot (0, 4 and 6): pos, neg, pos

Died of peri-operative complications;


The type of assay or the antigen is unknown. AE: Alveolar Echinococcosis; IHA: Indirect HemAgglutination.


The resection was performed for diagnostic purpose. MRI: Magnetic Resonance Imaging; CT: Computed Tomography; PET-CT: Positron Emission Tomography associated with Computed Tomography.

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