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Table 1

Baseline characteristics, clinical manifestations and outcomes of the eight SOT recipients with AE.

ID Sex; F: female; M: male Age at diagnosis Transplanted organ Time from transplant to diagnosis (in months)a Immunosuppressive regimen Clinical presentation Extension PNM stage Diagnostic delayb (in months) Comments
1 F 57 Lung 43 Prednisone, MMF, Tacrolimus Asymptomatic P1N0M0 (I) 1
2 F 53 Kidney (2×) 12a Prednisone, Tacrolimus Fever and pain in left hypochondrium Stomach and esophagus P1N1M0 (IIIb)
3 M 55 Kidney 91 MMF, Everolimus Pain in right hypochondrium P2N0M0 (I) 11 Radiological lesions not immediately investigated
4 F 62 Kidney (2×) 240a Prednisone, cyclosporine, azathioprine (switched to MMF) Asymptomatic P1N0M0 (I) 30 Radiological lesions not immediately investigated
5 F 66 Heart 117 Prednisone, MMF, cyclosporine Epigastric pain Head of pancreas P4N1M0 (IV)
6 F 59 Kidney 57 MMF, Tacrolimus Asymptomatic P0N0M1 (IV) 12 Initial misdiagnosis of tuberculosis
7 M 36 Kidney 75 Prednisone, MMF, Cyclosporine Asymptomatic P1N0M0 (I) 3 Initial misdiagnosis of metastasis
8 F 43 Lung 12 Prednisone, MMF, Tacrolimus Pain in right hypochondrium P1N1M0 (IIIb)

Time from the first transplantation to diagnosis.


Time from first evidence of a radiological lesion to final diagnosis. MMF: MycoPhenolate Mofetil.

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