Efficacy of NexGard® Combo against Amblyomma americanum.
|Study||Group||n||Arithmetic means (AM) of live ticks and % efficacy 72 h after treatment or subsequent infestations
|Day 3||Day 10||Day 17||Day 24||Day 33|
|p-value dead ticks||<0.0001||<0.0001||<0.0001||<0.0001||<0.0001|
|P-value Dead ticks||<0.0001||<0.0001||<0.0001||<0.0001||<0.0001|
Cats were treated topically once on Day 0, each with 0.12 mL/kg of the novel formulation, providing 1.44 mg/kg esafoxolaner, 0.48 mg/kg eprinomectin, and 10.0 mg/kg praziquantel.
Percent efficacy = 100[(C − T)/C], where T and C are arithmetic means (AM) of the novel formulation and control groups, respectively.
p-value = two-sided probability value from analysis of variance using the MIXED model to compare the novel formulation group with the control group.
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