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Table 4.

Evaluation of the clinical signs associated with demodicosis and hair regrowth during the 3-month study period.

Day -2 Day 27
Day 55
Day 84
Number of dogs with crusts or scales/total Number of dogs with crusts or scales/total Hair regrowth score* (number of dogs in each category)
Number of dogs with crusts or scales/total dogs Hair regrowth score (number of dogs in each category)
Number of dogs with crusts or scales Hair regrowth score (number of dogs in each category)
1 2 3 1 2 3 1 2 3
Group 1: combination of fipronil, amitraz, and (S)-methoprene (28 Days) 6/6 3/5* 4 1 0 2/5 0 5 0 0/5 0 0 5/5
Group 2: combination of fipronil, amitraz, and (S)-methoprene (14 Days) 6/6 4/6 3 3 0 6/6 0 5 1 3/6 0 0 6/6
Group 3: combination of amitraz and metaflumizone (28 Days) 5/6 4/6 3 1 2 2/6 0 3 3 1/6 0 1 5/6

Hair regrowth score = The skin surface of the dogs on which hair regrowth occurred, compared to pre-treatment observations, was scored as 1 if <50% hair regrowth occurred, 2 if 50–90% hair regrowth occurred, and 3 if >90% hair regrowth took place.

*

One of the group 1 dogs died at Day 12 for a reason not related to treatment.

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