Open Access
Table 3.
Individual Demodex counts for each dog at each evaluation and mean percentage of mite count reduction for each group.
| Day -2 | Day 27 | Day 55 | Day 84 | ||
|---|---|---|---|---|---|
| Group 1: combination of fipronil, amitraz, and (S)-methoprene at 28-day intervals | Dog 1* | 2,454 | - | - | - |
| Dog 2 | 796 | 0 | 10 | 2 | |
| Dog 3 | 443 | 115 | 191 | 2 | |
| Dog 4 | 238 | 15 | 0 | 0 | |
| Dog 5 | 158 | 12 | 0 | 0 | |
| Dog 6 | 68 | 0 | 0 | 0 | |
| Geometric mean | 361.7 | 6.5 | 3.6 | 0.6 | |
| Percent reduction | 97.4% | 98.5% | 99.8% | ||
| Group 2: combination of fipronil, amitraz, and (S)-methoprene at 14-day intervals | Dog 7 | 1,335 | 7 | 3 | 0 |
| Dog 8 | 722 | 129 | 1 | 0 | |
| Dog 9 | 504 | 69 | 0 | 0 | |
| Dog 10 | 368 | 0 | 0 | 0 | |
| Dog 11 | 77 | 0 | 0 | 0 | |
| Dog 12 | 20 | 1 | 0 | 0 | |
| Geometric mean | 257.0 | 6.3 | 0.4 | 0.0 | |
| Percent reduction | 97.6% | 99.8% | 100.0% | ||
| Group 3: combination of amitraz and metaflumizone at 28-day intervals | Dog 13 | 842 | 11 | 0 | 0 |
| Dog 14 | 615 | 2 | 1 | 0 | |
| Dog 15 | 436 | 16 | 0 | 0 | |
| Dog 16 | 327 | 1 | 0 | 0 | |
| Dog 17 | 68 | 5 | 0 | 0 | |
| Dog 18 | 9 | 1 | 0 | 0 | |
| Geometric mean | 191.8 | 3.9 | 0.1 | 0.0 | |
| Percent reduction | 97.9% | 99.9% | 100.0% |
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