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Research note

Table I.

AgB-specific IgG1/IgG2a reactivity index (R.I.) ratios in mice immunized with EgAgB8/2-DNA using different routes of inoculations. Serum samples were collected 50 days following initial inoculations and were assayed for AgB-specific IgG1 and IgG2a.

Route of inoculation R.I. ratio IgG1/IgG2a*
Intramuscular 0.04
Intranasal 0.25
Epidermal gene gun 0.58
*

Statistically significant differences in ratios were seen among the three routes.

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