Issue |
Parasite
Volume 19, Number 4, November 2012
|
|
---|---|---|
Page(s) | 441 - 444 | |
DOI | https://doi.org/10.1051/parasite/2012194441 | |
Published online | 15 November 2012 |
Research note
Histological and molecular biology diagnosis of neurocysticercosis in a patient without history of travel to endemic areas – Case report
Diagnostic histologique et moléculaire d’une neurocysticercose atypique chez un patient français n’ayant jamais voyagé en zone d’endémie
1
Parasitology department, University Hospital, Dijon, France
2
Pathology department, University Hospital, Dijon, France
3
Infectious diseases department, University Hospital, Dijon, France
4
Parasitology department, Centro Nacional de Microbiología, Madrid, Spain
5
Histotechnology and Pathology department, Institut Pasteur, Paris, France
6
University of Edinburgh, Royal (Dick) School of Veterinary Medicine, Easter Bush Veterinary Centre, The Sir Alexander Robertson Building, Easter Bush, Roslin, Midlothian, Scotland
* Correspondence: Frédéric Dalle, Département de Parasitologie Mycologie, Centre Hospitalier Universitaire de Dijon, 2, rue Angélique Ducoudray, 21000 Dijon, France. Tel.: 33 (3) 80 29 50 14 – Fax: 33 (3) 80 29 32 80. E-mail: frederic.dalle@u-bourgogne.fr
Received:
13
February
2012
Accepted:
11
June
2012
Background: in endemic areas, neurocysticercosis appears mainly as a single, large, spherical and non-enhancing intracranial cyst. Case presentation: an atypical case of neurocysticercosis (NCC) in a French Caucasian, without history of travel to endemic areas, was confirmed by histology and molecular speciation. Imaging was atypical, showing several hook-bearing scolices visible in the cyst, while the serology employed was non-contributary. Conclusions: NCC should be considered when multiple taeniid scolices are observed within the same cystic lesion.
Résumé
Contexte : en zone endémique, les lésions kystiques intra-crâniales de neurocysticercose sont classiquement uniques, étendues, sphériques et sans prise de contraste. Cas clinique : un cas atypique de neurocysticercose (NCC) chez un caucasien français n’ayant jamais voyagé en zone d’endémie a été confirmé par histologie et biologie moléculaire. L’imagerie était atypique, montrant plusieurs scolex surmontés de crochets et localisés au sein d’une même lésion kystique. La sérologie était non contributive pour le diagnostic. Conclusions : le diagnostic de NCC doit être évoqué lorsque plusieurs scolex sont observés au sein d’une même lésion kystique.
Key words: neurocysticercosis / Taenia solium / histology / molecular biology / French patient
Mots clés : neurocysticercose / Taenia solium / histologie / biologie moléculaire / patient français
© PRINCEPS Editions, Paris, 2012, transferred to Société Française de Parasitologie
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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