Open Access
Volume 29, 2022
Article Number 51
Number of page(s) 19
Published online 09 November 2022
  1. Adell T, Martín-Durán JM, Saló E, Cebrià F. 2015. Platyhelminthes, Evolutionary Developmental Biology of Invertebrates. Springer: Vienna. p. 21–40. [CrossRef] [Google Scholar]
  2. Aguirre-Fey D, Benítez-Villa GE, de Leon GPP, Rubio-Godoy M. 2015. Population dynamics of Cichlidogyrus spp. and Scutogyrus sp. (Monogenea) infecting farmed tilapia in Veracruz, México. Aquaculture, 443, 11–15. [CrossRef] [Google Scholar]
  3. Andree KB, Roque A, Duncan N, Gisbert E, Estevez A, Tsertou MI, Katharios P. 2015. Diplectanum sciaenae (Van Beneden & Hesse, 1863) (Monogenea) infecting meagre, Argyrosomus regius (Asso, 1801) broodstock in Catalonia, Spain. Veterinary Parasitology: Regional Studies and Reports, 1, 75–79. [CrossRef] [Google Scholar]
  4. Apweiler R, Bairoch A, Wu CH, Barker WC, Boeckmann B, Ferro S, Gasteiger E, Huang H, Lopez R, Magrane M, Martin MJ, Natale DA, O’Donovan C, Redaschi N, Yeh LSL. 2004. UniProt: the universal protein knowledgebase. Nucleic Acids Research, 32(suppl_1), D115–D119. [Google Scholar]
  5. Arensdorf AM, Marada S, Ogden SK. 2016. Smoothened regulation: a tale of two signals. Trends in Pharmacological Sciences, 37(1), 62–72. [CrossRef] [PubMed] [Google Scholar]
  6. Ayers KL, Thérond PP. 2010. Evaluating Smoothened as a G-protein-coupled receptor for Hedgehog signaling. Trends in Cell Biology, 20(5), 287–298. [CrossRef] [PubMed] [Google Scholar]
  7. Bahia D, Avelar L, Mortara RA, Khayath N, Yan Y, Noël C, Capron M, Dissous C, Pierce RJ, Oliveira G. 2006. SmPKC1, a new protein kinase C identified in the platyhelminth parasite Schistosoma mansoni. Biochemical and Biophysical Research Communications, 345(3), 1138–1148. [CrossRef] [PubMed] [Google Scholar]
  8. Bjarnadóttir TK, Fredriksson R, Schiöth HB. 2005. The gene repertoire and the common evolutionary history of glutamate, pheromone (V2R), taste (1) and other related G protein-coupled receptors. Gene, 362, 70–84. [CrossRef] [PubMed] [Google Scholar]
  9. Bockaert J, Fagni L, Dumuis A, Marin P. 2004. GPCR interacting proteins (GIP). Pharmacology & Therapeutics, 103(3), 203–221. [CrossRef] [PubMed] [Google Scholar]
  10. Bolger AM, Lohse M, Usadel B. 2014. Trimmomatic: a flexible trimmer for Illumina sequence data. Bioinformatics, 30(15), 2114–2120. [CrossRef] [PubMed] [Google Scholar]
  11. Bryant DM, Johnson K, DiTommaso T, Tickle T, Couger MB, Payzin-Dogru D, Lee TJ, Leigh ND, Kuo TH, Davis FG, Bateman J, Bryant S, Guzikowski AR, Tsai SL, Coyne S, Ye WW, Freeman RM, Peshkin L, Tabin CJ, Regev A, Haas BJ, Whited JL. 2017. A tissue-mapped axolotl de novo transcriptome enables identification of limb regeneration factors. Cell Reports, 18(3), 762–776. [CrossRef] [PubMed] [Google Scholar]
  12. Buchfink B, Xie C, Huson DH. 2015. Fast and sensitive protein alignment using DIAMOND. Nature Methods, 12(1), 59–60. [CrossRef] [PubMed] [Google Scholar]
  13. Buchmann K, Roepstorff A, Waller PJ. 1992. Experimental selection of mebendazole-resistant gill monogeneans from the European eel, Anguilla anguilla L. Journal of Fish Diseases, 15(5), 393–408. [CrossRef] [Google Scholar]
  14. Caffrey CR, Goupil L, Rebello KM, Dalton JP, Smith D. 2018. Cysteine proteases as digestive enzymes in parasitic helminths. PLoS Neglected Tropical Diseases, 12(8), e0005840. [PubMed] [Google Scholar]
  15. Camacho C, Coulouris G, Avagyan V, Ma N, Papadopoulos J, Bealer K, Madden TL. 2009. BLAST+: architecture and applications. BMC Bioinformatics, 10(1), 1–9. [CrossRef] [PubMed] [Google Scholar]
  16. Campos TD, Young ND, Korhonen PK, Hall RS, Mangiola S, Lonie A, Gasser RB. 2014. Identification of G protein-coupled receptors in Schistosoma haematobium and S. mansoni by comparative genomics. Parasites & Vectors, 7(1), 1–11. [CrossRef] [PubMed] [Google Scholar]
  17. Caña-Bozada V, Llera-Herrera R, Fajer-Ávila EJ, Morales-Serna FN. 2021. Mitochondrial genome of Rhabdosynochus viridisi (Monogenea: Diplectanidae), a parasite of Pacific white snook Centropomus viridis. Journal of Helminthology, 95, e21. [CrossRef] [PubMed] [Google Scholar]
  18. Caña-Bozada V, Llera-Herrera R, Fajer-Ávila EJ, Morales-Serna FN. 2021. Mitochondrial genome of Scutogyrus longicornis (Monogenea: Dactylogyridea), a parasite of Nile tilapia Oreochromis niloticus. Parasitology International, 81, 102281. [CrossRef] [PubMed] [Google Scholar]
  19. Capella-Gutiérrez S, Silla-Martínez JM, Gabaldón T. 2009. trimAl: a tool for automated alignment trimming in large-scale phylogenetic analyses. Bioinformatics, 25(15), 1972–1973. [CrossRef] [PubMed] [Google Scholar]
  20. Chase DL, Koelle MR. 2007. Biogenic amine neurotransmitters in C. elegans. WormBook, 20, 1–15. [Google Scholar]
  21. International Helminth Genomes Consortium. 2019. Comparative genomics of the major parasitic worms. Nature Genetics, 51(1), 163. [CrossRef] [PubMed] [Google Scholar]
  22. Cortés A, Mikeš L, Muñoz-Antolí C, Álvarez-Izquierdo M, Esteban JG, Horák P, Toledo R. 2019. Secreted cathepsin L-like peptidases are involved in the degradation of trapped antibodies on the surface of Echinostoma caproni. Parasitology Research, 118(12), 3377–3386. [CrossRef] [PubMed] [Google Scholar]
  23. Cribb TH, Chisholm LA, Bray RA. 2002. Diversity in the Monogenea and Digenea: does lifestyle matter? International Journal for Parasitology, 32(3), 321–328. [CrossRef] [PubMed] [Google Scholar]
  24. Dahl G, Muller KJ. 2014. Innexin and pannexin channels and their signaling. FEBS Letters, 588(8), 1396–1402. [CrossRef] [PubMed] [Google Scholar]
  25. Dezfuli BS, Giari L, Simoni E, Menegatti R, Shinn AP, Manera M. 2007. Gill histopathology of cultured European sea bass, Dicentrarchus labrax (L.), infected with Diplectanum aequans (Wagener 1857) Diesing 1958 (Diplectanidae: Monogenea). Parasitology Research, 100(4), 707–713. [CrossRef] [PubMed] [Google Scholar]
  26. Dissous C, Grevelding CG, Long T. 2011. Schistosoma mansoni Polo-like kinases and their function in control of mitosis and parasite reproduction. Anais da Academia Brasileira de Ciências, 83, 627–635. [CrossRef] [PubMed] [Google Scholar]
  27. Dissous C, Khayath N, Vicogne J, Capron M. 2006. Growth factor receptors in helminth parasites: signalling and host–parasite relationships. FEBS Letters, 580(12), 2968–2975. [CrossRef] [PubMed] [Google Scholar]
  28. Donnelly S, O’Neill SM, Stack CM, Robinson MW, Turnbull L, Whitchurch C, Dalton JP. 2010. Helminth cysteine proteases inhibit TRIF-dependent activation of macrophages via degradation of TLR3. Journal of Biological Chemistry, 285(5), 3383–3392. [CrossRef] [Google Scholar]
  29. Edgar RC. 2004. MUSCLE: multiple sequence alignment with high accuracy and high throughput. Bioinformatics, 32(5), 1792–1797. [Google Scholar]
  30. Elphick MR, Mirabeau O, Larhammar D. 2018. Evolution of neuropeptide signaling systems. Journal of Experimental Biology, 221(3), jeb151092. [CrossRef] [PubMed] [Google Scholar]
  31. Fang H, Gough J. 2013. DcGO: database of domain-centric ontologies on functions, phenotypes, diseases and more. Nucleic Acids Research, 41(D1), D536–D544. [CrossRef] [PubMed] [Google Scholar]
  32. Finn RD, Coggill P, Eberhardt RY, Eddy SR, Mistry J, Mitchell AL, Potter SC, Punta M, Qureshi M, Sangrador-Vegas A, Salazar GA, Bateman A. 2016. The Pfam protein families database: towards a more sustainable future. Nucleic Acids Research, 44(D1), D279–D285. [CrossRef] [PubMed] [Google Scholar]
  33. Fredriksson R, Lagerström MC, Lundin LG, Schiöth HB. 2003. The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints. Molecular Pharmacology, 63(6), 1256–1272. [CrossRef] [PubMed] [Google Scholar]
  34. Fu L, Niu B, Zhu Z, Wu S, Li W. 2012. CD-HIT: accelerated for clustering the next-generation sequencing data. Bioinformatics, 28(23), 3150–3152. [CrossRef] [PubMed] [Google Scholar]
  35. Gene Ontology Consortium. 2008. The gene ontology project in 2008. Nucleic Acids Research, 36(suppl_1), D440–D444. [CrossRef] [PubMed] [Google Scholar]
  36. Giuliani S, Silva AC, Borba JV, Ramos PI, Paveley RA, Muratov EN, Andrade CH, Furnham N. 2018. Computationally-guided drug repurposing enables the discovery of kinase targets and inhibitors as new schistosomicidal agents. PLoS Computational Biology, 14(10), e1006515. [CrossRef] [PubMed] [Google Scholar]
  37. Grabherr MG, Haas BJ, Yassour M, Levin JZ, Thompson DA, Amit I, Adiconis X, Fan L, Raychowdhury R, Zeng Q, Chen Z, Mauceli E, Hacohen N, Gnirke A, Rhind N, di Palma F, Birren BW, Nusbaum C, Lindblad-Toh K, Friedman N, Regev A. 2011. Full-length transcriptome assembly from RNA-Seq data without a reference genome. Nature Biotechnology, 29(7), 644–652. [CrossRef] [PubMed] [Google Scholar]
  38. Guidi A, Mansour NR, Paveley RA, Carruthers IM, Besnard J, Hopkins AL, Gilbert IH, Bickle QD. 2015. Application of RNAi to genomic drug target validation in schistosomes. PLoS Neglected Tropical Diseases, 5, e0003801. [CrossRef] [PubMed] [Google Scholar]
  39. Güiza J, Barría I, Sáez JC, Vega JL. 2018. Innexins: expression, regulation, and functions. Frontiers in Physiology, 9, 1414. [CrossRef] [PubMed] [Google Scholar]
  40. Haas BJ, Papanicolaou A, Yassour M, Grabherr M, Blood PD, Bowden J, Couger MB, Eccles D, Li B, Lieber M, MacManes MD, Ott M, Orvis J, Pochet N, Strozzi F, Weeks N, Westerman R, William T, Dewey CN, Henschel R, LeDuc RD, Friedman N, Regev A. 2013. De novo transcript sequence reconstruction from RNA-seq using the Trinity platform for reference generation and analysis. Nature Protocols, 8(8), 1494–1512. [CrossRef] [PubMed] [Google Scholar]
  41. Hahn C, Fromm B, Bachmann L. 2014. Comparative genomics of flatworms (Platyhelminthes) reveals shared genomic features of ecto-and endoparastic neodermata. Genome Biology and Evolution, 6(5), 1105–1117. [CrossRef] [PubMed] [Google Scholar]
  42. Hauser AS, Attwood MM, Rask-Andersen M, Schiöth HB, Gloriam DE. 2017. Trends in GPCR drug discovery: new agents, targets and indications. Nature Reviews Drug Discovery, 16(12), 829–842. [CrossRef] [PubMed] [Google Scholar]
  43. Hoai TD. 2020. Reproductive strategies of parasitic flatworms (Platyhelminthes, Monogenea): the impact on parasite management in aquaculture. Aquaculture International, 28(1), 421–447. [CrossRef] [Google Scholar]
  44. Hoai TD, Hutson KS. 2014. Reproductive strategies of the insidious fish ectoparasite, Neobenedenia sp. (Capsalidae: Monogenea). PLoS One, 9(9), e108801. [CrossRef] [PubMed] [Google Scholar]
  45. Houhou H, Puckelwaldt O, Strube C, Haeberlein S. 2019. Reference gene analysis and its use for kinase expression profiling in Fasciola hepatica. Scientific Reports, 9(1), 1–14. [CrossRef] [PubMed] [Google Scholar]
  46. Howe KL, Bolt BJ, Shafie M, Kersey P, Berriman M. 2017. WormBase ParaSite – a comprehensive resource for helminth genomics. Molecular and Biochemical Parasitology, 215, 2–10. [CrossRef] [PubMed] [Google Scholar]
  47. Huang HC, Klein PS. 2004. The Frizzled family: receptors for multiple signal transduction pathways. Genome Biology, 5(7), 1–7. [Google Scholar]
  48. Hübner CA, Jentsch TJ. 2002. Ion channel diseases. Human Molecular Genetics, 11(20), 2435–2445. [CrossRef] [PubMed] [Google Scholar]
  49. Huerta-Cepas J, Szklarczyk D, Forslund K, Cook H, Heller D, Walter MC, Rattei T, Mende DR, Sunagawa S, Kuhn M, Jensen LJ, von Mering C, Bork P. 2016. eggNOG 4.5: a hierarchical orthology framework with improved functional annotations for eukaryotic, prokaryotic and viral sequences. Nucleic Acids Research, 44(D1), D286–D293. [CrossRef] [PubMed] [Google Scholar]
  50. James CE, Hudson AL, Davey MW. 2009. Drug resistance mechanisms in helminths: Is it survival of the fittest? Trends in Parasitology, 25(7), 328–335. [CrossRef] [PubMed] [Google Scholar]
  51. Jedličková L, Dvořáková H, Dvořák J, Kašný M, Ulrychova L, Vorel J, Žárský V, Mikeš L. 2018. Cysteine peptidases of Eudiplozoon nipponicum: a broad repertoire of structurally assorted cathepsins L in contrast to the scarcity of cathepsins B in an invasive species of haematophagous monogenean of common carp. Parasites & Vectors, 11(1), 1–17. [CrossRef] [PubMed] [Google Scholar]
  52. Jerônimo GT, Speck GM, Cechinel MM, Gonçalves ELT, Martins ML. 2011. Seasonal variation on the ectoparasitic communities of Nile tilapia cultured in three regions in southern Brazil. Brazilian Journal of Biology, 71, 365–373. [CrossRef] [PubMed] [Google Scholar]
  53. Kalyaanamoorthy S, Minh BQ, Wong TK, Von Haeseler A, Jermiin LS. 2017. ModelFinder: fast model selection for accurate phylogenetic estimates. Nature Methods, 14(6), 587–589. [CrossRef] [PubMed] [Google Scholar]
  54. Kanehisa M, Goto S, Sato Y, Furumichi M, Tanabe M. 2012. KEGG for integration and interpretation of large-scale molecular data sets. Nucleic Acids Research, 40(D1), D109–D114. [CrossRef] [PubMed] [Google Scholar]
  55. Katoh K, Standley DM. 2013. MAFFT multiple sequence alignment software version 7: improvements in performance and usability. Molecular Biology and Evolution, 30(4), 772–780. [CrossRef] [Google Scholar]
  56. Kearn GC. 1967. Experiments on host-finding and host-specificity in the monogenean skin parasite Entobdella soleae. Parasitology, 57(3), 585–605. [CrossRef] [PubMed] [Google Scholar]
  57. Kearn GC. 1986. The eggs of monogeneans. Advances in Parasitology, 25, 175–273. [CrossRef] [PubMed] [Google Scholar]
  58. Kearn GC, Macdonald S. 1976. The chemical nature of host hatching factors in the monogenean skin parasites Entobdella soleae and Acanthocotyle lobianchi. International Journal for Parasitology, 6(6), 457–466. [CrossRef] [PubMed] [Google Scholar]
  59. Keating CD, Kriek N, Daniels M, Ashcroft NR, Hopper NA, Siney EJ, Siney EJ, Burke JF. 2003. Whole-genome analysis of 60 G protein-coupled receptors in Caenorhabditis elegans by gene knockout with RNAi. Current Biology, 13(19), 1715–1720. [CrossRef] [PubMed] [Google Scholar]
  60. Kerfeld CA, Scott KM. 2011. Using BLAST to teach “E-value-tionary” concepts. PLoS Biology, 9(2), e1001014. [CrossRef] [PubMed] [Google Scholar]
  61. Konczal M, Przesmycka KJ, Mohammed RS, Phillips KP, Camara F, Chmielewski S, Hahn C, Guigo R, Cable J, Radwan J. 2020. Gene duplications, divergence and recombination shape adaptive evolution of the fish ectoparasite Gyrodactylus bullatarudis. Molecular Ecology, 29(8), 1494–1507. [CrossRef] [PubMed] [Google Scholar]
  62. Koziol U, Koziol M, Preza M, Costábile A, Brehm K, Castillo E. 2016. De novo discovery of neuropeptides in the genomes of parasitic flatworms using a novel comparative approach. International Journal for Parasitology, 46(11), 709–721. [CrossRef] [PubMed] [Google Scholar]
  63. Krogh A, Larsson B, Von Heijne G, Sonnhammer EL. 2001. Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes. Journal of Molecular Biology, 305(3), 567–580. [CrossRef] [PubMed] [Google Scholar]
  64. Kumkate S, Chunchob S, Janvilisri T. 2008. Expression of ATP-binding cassette multidrug transporters in the giant liver fluke Fasciola gigantica and their possible involvement in the transport of bile salts and anthelmintics. Molecular and Cellular Biochemistry, 317(1), 77–84. [CrossRef] [PubMed] [Google Scholar]
  65. Langenhan T, Aust G, Hamann J. 2013. Sticky signaling – Adhesion class G protein–coupled receptors take the stage. Science Signaling, 6(276), re3. [CrossRef] [PubMed] [Google Scholar]
  66. Langmead B, Salzberg SL. 2012. Fast gapped-read alignment with Bowtie 2. Nature Methods, 9(4), 357–359. [CrossRef] [PubMed] [Google Scholar]
  67. Laumer CE, Hejnol A, Giribet G. 2015. Nuclear genomic signals of the ‘microturbellarian’ roots of platyhelminth evolutionary innovation. eLife, 4, e05503. [CrossRef] [Google Scholar]
  68. Lee HG, Seong CS, Kim YC, Davis RL, Han KA. 2003. Octopamine receptor OAMB is required for ovulation in Drosophila melanogaster. Developmental Biology, 264(1), 179–190. [CrossRef] [PubMed] [Google Scholar]
  69. Lee IH, Procko C, Lu Y, Shaham S. 2021. Stress-Induced neural plasticity mediated by glial GPCR REMO-1 promotes C. elegans adaptive behavior. Cell Reports, 34(2), 108607. [CrossRef] [PubMed] [Google Scholar]
  70. Li H, Handsaker B, Wysoker A, Fennell T, Ruan J, Homer N, Marth G, Abecasis G, Durbin R. 2009. The sequence alignment/map format and SAMtools. Bioinformatics, 25(16), 2078–2079. [CrossRef] [PubMed] [Google Scholar]
  71. Liang D, Zhao M, Wang T, McManus DP, Cummins SF. 2016. GPCR and IR genes in Schistosoma mansoni miracidia. Parasites & Vectors, 9(1), 1–12. [CrossRef] [PubMed] [Google Scholar]
  72. Lim J, Sabandal PR, Fernandez A, Sabandal JM, Lee HG, Evans P, Han KA. 2014. The octopamine receptor Octβ2R regulates ovulation in Drosophila melanogaster. PloS One, 9(8), e104441. [CrossRef] [PubMed] [Google Scholar]
  73. Lok JB. 2016. Signaling in parasitic nematodes: physicochemical communication between host and parasite and endogenous molecular transduction pathways governing worm development and survival. Current Clinical Microbiology Reports, 3(4), 186–197. [CrossRef] [PubMed] [Google Scholar]
  74. MacDonald K, Kimber MJ, Day TA, Ribeiro P. 2015. A constitutively active G protein-coupled acetylcholine receptor regulates motility of larval Schistosoma mansoni. Molecular and Biochemical Parasitology, 202(1), 29–37. [CrossRef] [PubMed] [Google Scholar]
  75. MacDonald S, Jones A. 1978. Egg-laying and hatching rhythms in the monogenean Diplozoon homoion gracile from the southern barbel (Barbus meridionalis). Journal of Helminthology, 52(1), 23–28. [CrossRef] [PubMed] [Google Scholar]
  76. Manglik A, Kobilka B. 2014. The role of protein dynamics in GPCR function: insights from the β2AR and rhodopsin. Current Opinion in Cell Biology, 27, 136–143. [CrossRef] [PubMed] [Google Scholar]
  77. Manning G, Whyte DB, Martinez R, Hunter T, Sudarsanam S. 2002. The protein kinase complement of the human genome. Science, 298(5600), 1912–1934. [CrossRef] [PubMed] [Google Scholar]
  78. Marks NJ, Maule AG. 2010. Neuropeptides in helminths: occurrence and distribution, in Neuropeptide Systems as Targets for Parasite and Pest Control. Advances in Experimental Medicine and Biology, Vol. 692. Geary TG, Maule AG, Editors. Springer: New York, NY. p. 49–77. [Google Scholar]
  79. McVeigh P. 2020. Post-genomic progress in helminth parasitology. Parasitology, 147(8), 835–840. [CrossRef] [PubMed] [Google Scholar]
  80. McVeigh P, Kimber MJ, Novozhilova E, Day TA. 2005. Neuropeptide signaling systems in flatworms. Parasitology, 131(S1), S41–S55. [Google Scholar]
  81. McVeigh P, McCusker P, Robb E, Wells D, Gardiner E, Mousley A, Marks NJ, Maule AG. 2018. Reasons to be nervous about flukicide discovery. Trends in Parasitology, 34(3), 184–196. [CrossRef] [PubMed] [Google Scholar]
  82. McVeigh P, McCammick E, McCusker P, Wells D, Hodgkinson J, Paterson S, Mousleya A, Marks NJ, Maule AG. 2018. Profiling G protein-coupled receptors of Fasciola hepatica identifies orphan rhodopsins unique to phylum Platyhelminthes. International Journal for Parasitology: Drugs and Drug Resistance, 8(1), 87–103. [CrossRef] [Google Scholar]
  83. Montero-Mendieta S, Grabherr M, Lantz H, De la Riva I, Leonard JA, Webster MT, Vilà C. 2017. A practical guide to build de-novo assemblies for single tissues of non-model organisms: the example of a Neotropical frog. PeerJ, 5, e3702. [CrossRef] [PubMed] [Google Scholar]
  84. Morales-Serna FN, López-Moreno DG, Medina-Guerrero RM, Abad-Rosales SM, Martínez-Brown JM, Ibarra-Castro L, Fajer-Avila EJ. 2020. Toxicity of formalin for juvenile Centropomus viridis and in vitro efficacy against the parasite Rhabdosynochus sp. (Monogenea: Diplectanidae). Journal of Applied Ichthyology, 36(5), 740–744. [CrossRef] [Google Scholar]
  85. Morita M, Hall F, Best JB, Gern W. 1987. Photoperiodic modulation of cephalic melatonin in planarians. Journal of Experimental Zoology, 241(3), 383–388. [CrossRef] [PubMed] [Google Scholar]
  86. Nguyen LT, Schmidt HA, Von Haeseler A, Minh BQ. 2015. IQ-TREE: a fast and effective stochastic algorithm for estimating maximum-likelihood phylogenies. Molecular Biology and Evolution, 32(1), 268–274. [CrossRef] [PubMed] [Google Scholar]
  87. Nordström KJ, Lagerström MC, Wallér LM, Fredriksson R, Schiöth HB. 2009. The Secretin GPCRs descended from the family of Adhesion GPCRs. Molecular Biology and Evolution, 26(1), 71–84. [Google Scholar]
  88. Ogawa K. 2015. Diseases of cultured marine fishes caused by Platyhelminthes (Monogenea, Digenea, Cestoda). Parasitology, 142(1), 178–195. [CrossRef] [PubMed] [Google Scholar]
  89. Overington JP, Al-Lazikani B, Hopkins AL. 2006. How many drug targets are there? Nature Reviews Drug Discovery, 5(12), 993–996. [CrossRef] [PubMed] [Google Scholar]
  90. Oviedo NJ, Morokuma J, Walentek P, Kema IP, Gu MB, Ahn JM, Hwang JS, Gojobori T, Levin M. 2010. Long-range neural and gap junction protein-mediated cues control polarity during planarian regeneration. Developmental Biology, 339(1), 188–199. [CrossRef] [PubMed] [Google Scholar]
  91. Patocka N, Sharma N, Rashid M, Ribeiro P. 2014. Serotonin signaling in Schistosoma mansoni: A Serotonin–activated G protein-coupled receptor controls parasite movement. PLoS Pathogens, 10(1), e1003878. [CrossRef] [PubMed] [Google Scholar]
  92. Petersen TN, Brunak S, Von Heijne G, Nielsen H. 2011. SignalP 4.0: discriminating signal peptides from transmembrane regions. Nature Methods, 8(10), 785–786. [CrossRef] [PubMed] [Google Scholar]
  93. Rao YZ, Yang TB. 2007. cDNA cloning, mRNA expression and recombinant expression of a cathepsin L-like cysteine protease from Neobenedenia melleni (Monogenea: Capsalidae). Aquaculture., 269(1–4), 41–53. [CrossRef] [Google Scholar]
  94. Ribeiro P, Geary TG. 2010. Neuronal signaling in schistosomes: current status and prospects for postgenomics. Canadian Journal of Zoology, 88(1), 1–22. [CrossRef] [Google Scholar]
  95. Robinson MW, Tort JF, Lowther J, Donnelly SM, Wong E, Xu W, Stack CM, Padula M, Herbert B, Dalton JP. 2008. Proteomics and phylogenetic analysis of the cathepsin L protease family of the helminth pathogen Fasciola hepatica: expansion of a repertoire of virulence-associated factors. Molecular and Cellular Proteomics, 7(6), 1111–1123. [CrossRef] [Google Scholar]
  96. Saberi A, Jamal A, Beets I, Schoofs L, Newmark PA. 2016. GPCRs direct germline development and somatic gonad function in planarians. PLoS Biolpgy, 14(5), e1002457. [CrossRef] [Google Scholar]
  97. Santos BM, Dias BK, Nakabashi M, Garcia CR. 2021. The knockout for G Protein-Coupled Receptor-Like PfSR25 increases the susceptibility of malaria parasites to the antimalarials lumefantrine and piperaquine but not to medicine for malaria venture compounds. Frontiers in Microbiology, 12, 638869. [CrossRef] [PubMed] [Google Scholar]
  98. Seppey M, Manni M, Zdobnov EM. 2019. BUSCO: assessing genome assembly and annotation completeness. Gene Prediction, 1962, 227–245. [Google Scholar]
  99. Stoltzfus JD, Minot S, Berriman M, Nolan TJ, Lok JB. 2012. RNAseq analysis of the parasitic nematode Strongyloides stercoralis reveals divergent regulation of canonical dauer pathways. PLoS Neglected Tropical Diseases, 6(10), e1854. [CrossRef] [PubMed] [Google Scholar]
  100. Taman A, Ribeiro P. 2009. Investigation of a dopamine receptor in Schistosoma mansoni: functional studies and immunolocalization. Molecular and Biochemical Parasitology, 168(1), 24–33. [CrossRef] [PubMed] [Google Scholar]
  101. Tatusov RL, Galperin MY, Natale DA, Koonin EV. 2000. The COG database: a tool for genome-scale analysis of protein functions and evolution. Nucleic Acids Research, 28(1), 33–36. [CrossRef] [PubMed] [Google Scholar]
  102. Van Bel M, Proost S, Van Neste C, Deforce D, Van de Peer Y, Vandepoele K. 2013. TRAPID: an efficient online tool for the functional and comparative analysis of de novo RNA-Seq transcriptomes. Genome Biology, 14(12), 1–10. [Google Scholar]
  103. Vega JL, Subiabre M, Figueroa F, Schalper KA, Osorio L, González J, Sáez JC. 2013. Role of gap junctions and hemichannels in parasitic infections. BioMed Research International, 2013, 589130. [PubMed] [Google Scholar]
  104. Vorel J, Cwiklinski K, Roudnický P, Ilgová J, Jedličková L, Dalton JP, Mikeš L, Gelnar M, Kašný M. 2021. Eudiplozoon nipponicum (Monogenea, Diplozoidae) and its adaptation to haematophagy as revealed by transcriptome and secretome profiling. BMC Genomics, 22(1), 1–17. [CrossRef] [PubMed] [Google Scholar]
  105. Watanabe M. 2017. Gap junction in the teleost fish lineage: duplicated connexins may contribute to skin pattern formation and body shape determination. Frontiers in Cell and Development Biology, 5, 13. [CrossRef] [Google Scholar]
  106. Waterhouse RM, Seppey M, Simão FA, Manni M, Ioannidis P, Klioutchnikov G, Kriventseva EV, Zdobnov EM. 2018. BUSCO applications from quality assessments to gene prediction and phylogenomics. Molecular Biology and Evolution, 35(3), 543–548. [CrossRef] [PubMed] [Google Scholar]
  107. Wolstenholme AJ. 2011. Ion channels and receptor as targets for the control of parasitic nematodes. International Journal for Parasitology: Drugs and Drug Resistance, 1(1), 2–13. [CrossRef] [Google Scholar]
  108. Wolstenholme AJ, Fairweather I, Prichard R, von Samson-Himmelstjerna G, Sangster NC. 2004. Drug resistance in veterinary helminths. Trends in Parasitology, 20(10), 469–476. [CrossRef] [PubMed] [Google Scholar]
  109. Yermakova ON, Yermakov AM, Tiras KP, Lednev VV. 2009. Melatonin effect on the regeneration of the flatworm Girardia tigrina. Russian Journal of Developmental Biology, 40(6), 382–385. [CrossRef] [Google Scholar]
  110. Yu G, Smith DK, Zhu H, Guan Y, Lam TTY. 2017. ggtree: an R package for visualization and annotation of phylogenetic trees with their covariates and other associated data. Methods in Ecology and Evolution, 8(1), 28–36. [CrossRef] [Google Scholar]
  111. Zamanian M, Kimber MJ, McVeigh P, Carlson SA, Maule AG, Day TA. 2011. The repertoire of G protein-coupled receptors in the human parasite Schistosoma mansoni and the model organism Schmidtea mediterranea. BMC Genomics, 12(1), 1–21. [CrossRef] [Google Scholar]
  112. Zhang S, Zhi T, Xu X, Zheng Y, Bilong CFB, Pariselle A, Yang T. 2019. Monogenean fauna of alien tilapias (Cichlidae) in south China. Parasite, 26. [Google Scholar]
  113. Zhang Z, Wu J, Yu J, Xiao J. 2013. A brief review on the evolution of GPCR: conservation and diversification. Open Journal of Genetics, 2(04), 11. [Google Scholar]

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