Open Access
Review
Issue
Parasite
Volume 23, 2016
Article Number 15
Number of page(s) 10
DOI https://doi.org/10.1051/parasite/2016015
Published online 24 March 2016
  1. Akirav EM, Preston-Hurlburt P, Garyu J, Henegariu O, Clynes R, Schmidt AM, Herold KC. 2012. RAGE expression in human T cells: a link between environmental factors and adaptive immune responses. PLoS ONE, 7, e34698. [CrossRef] [PubMed] [Google Scholar]
  2. Alleva LM, Yang H, Tracey KJ, Clark IA. 2005. High mobility group box 1 (HMGB1) protein: possible amplification signal in the pathogenesis of falciparum malaria. Transactions of the Royal Society of Tropical Medicine and Hygiene, 99, 171–174. [CrossRef] [PubMed] [Google Scholar]
  3. Angeletti D, Kiwuwa MS, Byarugaba J, Kironde F, Wahlgren M. 2013. Elevated levels of High-Mobility Group Box-1 (HMGB1) in patients with severe or uncomplicated Plasmodium falciparum malaria. American Journal of Tropical Medicine and Hygiene, 88, 733–735. [CrossRef] [Google Scholar]
  4. Arama C, Giusti P, Boström S, Dara V, Traore B, Dolo A, Doumbo O, Varani S, Troye-Blomberg M. 2011. Interethnic differences in antigen-presenting cell activation and TLR Responses in Malian children during Plasmodium falciparum malaria. PLoS ONE, 6, e18319. [CrossRef] [PubMed] [Google Scholar]
  5. Arama C, Maiga B, Dolo A, Kouriba B, Traoré B, Crompton PD, Pierce SK, Troye-Blomberg M, Miller LH, Doumbo OK. 2015. Ethnic differences in susceptibility to malaria: What have we learned from immuno-epidemiological studies in West Africa? Acta Tropica, 146, 152–156. [CrossRef] [PubMed] [Google Scholar]
  6. Basta G. 2008. Receptor for advanced glycation endproducts and atherosclerosis: from basic mechanisms to clinical implications. Atherosclerosis, 196, 9–21. [CrossRef] [PubMed] [Google Scholar]
  7. Basta G, Schmidt AM, De Caterina R. 2004. Advanced glycation end products and vascular inflammation: implications for accelerated atherosclerosis in diabetes. Cardiovascular Research, 63, 582–592. [CrossRef] [PubMed] [Google Scholar]
  8. Becker K, Tilley L, Vennerstrom JL, Roberts D, Rogerson S, Ginsburg H. 2004. Oxidative stress in malaria parasite-infected erythrocytes: host-parasite interactions. International Journal for Parasitology, 34, 163–189. [CrossRef] [PubMed] [Google Scholar]
  9. Bierhaus A, Stern DM, Nawroth PP. 2006. RAGE in inflammation: a new therapeutic target? Current Opinion in Investigational Drugs, 7, 985–991. [Google Scholar]
  10. Bopp C, Bierhaus A, Hofer S, Bouchon A, Nawroth PP, Martin E, Weigand MA. 2008. Bench-to-bedside review: the inflammation-perpetuating pattern-recognition receptor RAGE as a therapeutic target in sepsis. Critical Care, 12, 201. [CrossRef] [Google Scholar]
  11. Bostrom S, Giusti P, Arama C, Persson JO, Dara V, Traore B, Dolo A, Doumbo O, Troye-Blomberg M. 2012. Changes in the levels of cytokines, chemokines and malaria-specific antibodies in response to Plasmodium falciparum infection in children living in sympatry in Mali. Malaria Journal, 11, 109. [CrossRef] [PubMed] [Google Scholar]
  12. Carter LM, Kafsack BFC, Llinas M, Mideo N, Pollitt LC, Reece SE. 2013. Stress and sex in malaria parasites: Why does commitment vary? Evolution Medicine and Public Health, 2013, 135–147. [CrossRef] [Google Scholar]
  13. Cavaillon JM, Adib-Conquy M. 2006. Bench-to-bedside review: endotoxin tolerance as a model of leukocyte reprogramming in sepsis. Critical Care, 10, 233. [CrossRef] [Google Scholar]
  14. Cerami A, Vlassara H, Brownlee M. 1988. Role of advanced glycosylation products in complications of diabetes. Diabetes Care, 11. Suppl, 1, 73–79. [Google Scholar]
  15. Chen GY, Nuñez G. 2010. Sterile inflammation: sensing and reacting to damage. Nature Review Immunology, 10, 826–837. [CrossRef] [Google Scholar]
  16. Chen Y, Yan SS, Colgan J, Zhang HP, Luban J, Schmidt AM, Stern D, Herold KC. 2004. Blockade of late stages of autoimmune diabetes by inhibition of the receptor for advanced glycation end products. Journal of Immunology, 173, 1399–1405. [CrossRef] [Google Scholar]
  17. Christaki E, Lazaridis N, Opal SM. 2012. Receptor for advanced glycation end products in bacterial infection: is there a role for immune modulation of receptor for advanced glycation end products in the treatment of sepsis? Current Opinion in Infectious Diseases, 25, 304–311. [CrossRef] [PubMed] [Google Scholar]
  18. Clark IA, Budd AC, Alleva LM, Cowden WB. 2006. Human malarial disease: a consequence of inflammatory cytokine release. Malaria Journal, 5, 85. [CrossRef] [PubMed] [Google Scholar]
  19. Cornet S, Bichet C, Larcombe S, Faivre B, Sorci G. 2014. Impact of host nutritional status on infection dynamics and parasite virulence in a bird-malaria system. Journal of Animal Ecology, 83, 256–265. [CrossRef] [Google Scholar]
  20. De Lumley H. 2006. Il y a 400 000 ans : la domestication du feu, un formidable moteur d’hominisation. Comptes Rendus Palevol, 5, 149–154. [CrossRef] [Google Scholar]
  21. Dolo A, Modiano D, Maiga B, Daou M, Dolo G, Guindo H, Ba M, Maiga H, Coulibaly D, Perlman H, Blomberg MT, Touré YT, Coluzzi M, Doumbo O. 2005. Difference in susceptibility to malaria between two sympatric ethnic groups in Mali. American Journal of Tropical Medicine and Hygiene, 72, 243–248. [Google Scholar]
  22. Dolo A, Coulibaly M, Maïga B, Daou M, Arama C, Troye-Blomberg M, Doumbo O. 2012. Réponse humorale anti-Plasmodium falciparum AMA1 et MSP1 dans deux groupes ethniques vivant en sympatrie au Mali. Bulletin de la Société de Pathologie Exotique, 105, 364–369. [CrossRef] [Google Scholar]
  23. Farouk SE, Dolo A, Bereczky S, Kouriba B, Maiga B, Färnert A, Perlmann H, Hayano M, Montgomery SM, Doumbo OK, Troye-Blomberg M. 2005. Different antibody and cytokine-mediated responses to Plasmodium falciparum parasite in two sympatric ethnic tribes living in Mali. Microbes and Infection, 7, 110–117. [CrossRef] [Google Scholar]
  24. Gangoiti MV, Cortizo AM, Arnol V, Felice JI, McCarthy AD. 2008. Opposing effects of bisphosphonates and advanced glycation endproducts on osteoblastic cells. European Journal of Pharmacology, 600, 140–147. [CrossRef] [PubMed] [Google Scholar]
  25. Goldberg T, Cai W, Peppa M, Dardaine V, Baliga BS, Uribarri J, Vlassara H. 2004. Advanced glycoxidation end products in commonly consumed foods. Journal of American Dietetic Association, 104, 1287–1291. [CrossRef] [Google Scholar]
  26. Golenser J, Chevion M. 1989. Oxidant stress and malaria: host-parasite interrelationships in normal and abnormal erythrocytes. Seminars in Hematology, 26, 313–325. [PubMed] [Google Scholar]
  27. González I, Romero J, Rodríguez BL, Pérez-Castro R, Rojas A. 2013. The immunobiology of the receptor of advanced glycation endproducts: trends and challenges. immunobiology, 218, 790–797. [CrossRef] [PubMed] [Google Scholar]
  28. Han SH, Kim YH, Mook-Jung I. 2011. RAGE: the beneficial and deleterious effects by diverse mechanisms of actions. Molecules and Cells, 31, 91–97. [CrossRef] [PubMed] [Google Scholar]
  29. Henle T. 2003. AGEs in foods: do they play a role in uremia? Kidney International Supplement, S145–147. [CrossRef] [Google Scholar]
  30. Higgins SJ, Xing K, Kim H, Kain DC, Wang F, Dhabangi A, Musoke C, Cserti-Gazdewich CM, Tracey KJ, Kain KC, Liles WW. 2013. Systemic release of high mobility group box 1 (HMGB1) protein is associated with severe and fatal Plasmodium falciparum malaria. Malaria Journal, 12, 105. [CrossRef] [PubMed] [Google Scholar]
  31. Hudson BI, Stickland MH, Futers TS, Grant PJ. 2001. Effects of novel polymorphisms in the RAGE gene on transcriptional regulation and their association with diabetic retinopathy. Diabetes, 50, 1505–1511. [CrossRef] [PubMed] [Google Scholar]
  32. Hunt NH, Stocker R. 1990. Oxidative stress and the redox status of malaria-infected erythrocytes. Blood Cells, 16, 499–526. [PubMed] [Google Scholar]
  33. Ibrahim MA, Isah MB, Okafor AI, Bashir M, Bisalla M, Umar IA. 2012. Effects of combined administration of vitamins C and E on some Plasmodium berghei-induced pathological changes and oxidative stress in mice. Comparative Clinical Pathology, 21, 1677–1682. [CrossRef] [Google Scholar]
  34. Isah MB, Ibrahim MA. 2014. The role of antioxidants treatment on the pathogenesis of malarial infections: a review. Parasitology Research, 113, 801–809. [CrossRef] [PubMed] [Google Scholar]
  35. Israelsson E, Vafa M, Maiga B, Lysén A, Iriemenam NC, Dolo A, Doumbo OK, Troye-Blomberg M, Berzins K. 2008. Differences in Fc gamma receptor IIa genotypes and IgG subclass pattern of anti-malarial antibodies between sympatric ethnic groups in Mali. Malaria Journal, 7, 175. [CrossRef] [PubMed] [Google Scholar]
  36. Israelsson E, Ekström M, Nasr A, Dolo A, Kearsley S, Arambepola G, Homann MV, Maiga B, Doumbo OK, Elghazali G, Giha HA, Troye-Blomberg M, Berzins K, Tornvall P. 2009. Marked differences in CRP genotype frequencies between the Fulani and sympatric ethnic groups in Africa. Malaria Journal, 8, 136. [CrossRef] [PubMed] [Google Scholar]
  37. Israelsson E, Maiga B, Kearsley S, Dolo A, Homann MV, Doumbo OK, Troye-Blomberg M, Tornvall P, Berzins K. 2011. Cytokine gene haplotypes with a potential effect on susceptibility to malaria in sympatric ethnic groups in Mali. Infection, Genetics and Evolution, 11, 1608–1615. [CrossRef] [Google Scholar]
  38. Jeong SJ, Lim BJ, Park S, Choi D, Kim HW, Ku NS, Han SH, Kim CO, Choi JY, Song YG, Kim JM. 2012. The effect of sRAGE-Fc fusion protein attenuates inflammation and decreases mortality in a murine cecal ligation and puncture model. Inflammation Research, 61, 1211–1218. [CrossRef] [Google Scholar]
  39. Karlsson EK, Kwiatkowski DP, Sabeti PC. 2014. Natural selection and infectious disease in human populations. Nature Review Genetics, 15, 379–393. [CrossRef] [PubMed] [Google Scholar]
  40. Kumar K, Singal A, Rizvi MMA, Chauhan VS. 2008. High mobility group box (HMGB) proteins of Plasmodium falciparum: DNA binding proteins with pro-inflammatory activity. Parasitology International, 57, 150–157. [CrossRef] [PubMed] [Google Scholar]
  41. Kwiatkowski DP. 2005. How malaria has affected the human genome and what human genetics can teach us about malaria. American Journal of Human Genetics, 77, 171–192. [CrossRef] [PubMed] [Google Scholar]
  42. Lien SC, Chang SF, Lee PL, Wei SY, Chang MDT, Chang JY, Chiu JJ. 2013. Mechanical regulation of cancer cell apoptosis and autophagy: roles of bone morphogenetic protein receptor, Smad1/5, and p38 MAPK. Biochimica et Biophysica Acta, 1833, 3124–3133. [CrossRef] [PubMed] [Google Scholar]
  43. Lokki AI, Järvelä I, Israelsson E, Maiga B, Troye-Blomberg M, Dolo A, Doumbo OK, Meri S, Holmberg V. 2011. Lactase persistence genotypes and malaria susceptibility in Fulani of Mali. Malaria Journal, 10, 9. [CrossRef] [PubMed] [Google Scholar]
  44. Lulli P, Mangano VD, Onori A, Batini C, Luoni G, Sirima BS, Nebie I, Chessa L, Petrarca V, Modiano D. 2009. HLA-DRB1 and -DQB1 loci in three West African ethnic groups: genetic relationship with sub-Saharan African and European populations. Human Immunology, 70, 903–909. [CrossRef] [PubMed] [Google Scholar]
  45. Maiga B, Dolo A, Touré O, Dara V, Tapily A, Campino S, Sepulveda N, Corran P, Rockett K, Clark TG, Blomberg MT, Doumbo OK. 2014. Fc gamma receptor IIa-H131R polymorphism and malaria susceptibility in sympatric ethnic groups, Fulani and Dogon of Mali. Scandinavian Journal of Immunology, 79, 43–50. [CrossRef] [PubMed] [Google Scholar]
  46. Martinez PJ, Mathews C, Actor JK, Hwang SA, Brown EL, De Santiago HK, Fisher Hoch SP, McCormick JB, Mirza S. 2014. Impaired CD4+ and T-helper 17 cell memory response to Streptococcus pneumoniae is associated with elevated glucose and percent glycated hemoglobin A1c in Mexican Americans with type 2 diabetes mellitus. Translational Research, 163, 53–63. [CrossRef] [Google Scholar]
  47. Matsumoto H, Matsumoto N, Ogura H, Shimazaki J, Yamakawa K, Yamamoto K, Shimazu T. 2015. The clinical significance of circulating soluble RAGE in patients with severe sepsis. Journal of Trauma and Acute Care Surgery, 78, 1086–1093. [Google Scholar]
  48. Mbugi EV, Meijerink M, Veenemans J, Jeurink PV, McCall M, Olomi RM, Shao JF, Chilongola JO, Verhoef H, Savelkoul HF. 2010. Effect of nutrient deficiencies on in vitro Th1 and Th2 cytokine response of peripheral blood mononuclear cells to Plasmodium falciparum infection. Malaria Journal, 9, 162. [CrossRef] [PubMed] [Google Scholar]
  49. Monteleone I, Rizzo A, Sarra M, Sica G, Sileri P, Biancone L, MacDonald TT, Pallone F, Monteleone G. 2011. Aryl hydrocarbon receptor-induced signals up-regulate IL-22 production and inhibit inflammation in the gastrointestinal tract. Gastroenterology, 141, 237–248. [CrossRef] [PubMed] [Google Scholar]
  50. Moser B, Desai DD, Downie MP, Chen Y, Yan SF, Herold K, Schmidt AM, Clynes R. 2007. Receptor for advanced glycation end products expression on T cells contributes to antigen-specific cellular expansion in vivo. Journal of Immunology, 179, 8051–8058. [CrossRef] [Google Scholar]
  51. Mosquera JA. 2010. Role of the receptor for advanced glycation end products (RAGE) in inflammation. Investigacion Clínica, 51, 257–268. [Google Scholar]
  52. Ott C, Jacobs K, Haucke E, Navarrete Santos A, Grune T, Simm A. 2014. Role of advanced glycation end products in cellular signaling. Redox Biology, 2, 411–429. [CrossRef] [PubMed] [Google Scholar]
  53. Perdijk O, Arama C, Giusti P, Maiga B, Troye-Blomberg M, Dolo A, Doumbo O, Persson JO, Boström S. 2013. Haptoglobin phenotype prevalence and cytokine profiles during Plasmodium falciparum infection in Dogon and Fulani ethnic groups living in Mali. Malaria Journal, 12, 432. [CrossRef] [PubMed] [Google Scholar]
  54. Poulsen MW, Hedegaard RV, Andersen JM, de Courten B, Bügel S, Nielsen J, Skibsted LH, Dragsted LO. 2013. Advanced glycation endproducts in food and their effects on health. Food and Chemical Toxicology, 60, 10–37. [CrossRef] [Google Scholar]
  55. Pradhan V, Ghosh K. 2012. Immunological disturbances associated with malarial infection. Journal of Parasitic Diseases, 37, 11–15. [Google Scholar]
  56. Quintana FJ, Basso AS, Iglesias AH, Korn T, Farez MF, Bettelli E, Caccamo M, Oukka M, Weiner HL. 2008. Control of T(reg) and T(H)17 cell differentiation by the aryl hydrocarbon receptor. Nature, 453, 65–71. [CrossRef] [PubMed] [Google Scholar]
  57. Rowe JA, Opi DH, Williams TN. 2009. Blood groups and malaria: fresh insights into pathogenesis and identification of targets for intervention. Current Opinion in Hematology, 16, 480–487. [CrossRef] [PubMed] [Google Scholar]
  58. RTS, S Clinical Trials Partnership. 2014. Efficacy and safety of the RTS, S/AS01 malaria vaccine during 18 months after vaccination: a phase 3 randomized, controlled trial in children and young infants at 11 African sites. PLoS Medicine, 11, e1001685. [CrossRef] [PubMed] [Google Scholar]
  59. Schlienger JL, Gautier M, Gutmann A, Kremer F. 2010. Produits terminaux de la glycation (AGE) alimentaires et pathologie métabolique. Médecine des Maladies Métaboliques, 4, 653–659. [CrossRef] [Google Scholar]
  60. Sell DR. 1997. Ageing promotes the increase of early glycation Amadori product as assessed by epsilon-N-(2-furoylmethyl)-L-lysine (furosine) levels in rodent skin collagen. The relationship to dietary restriction and glycoxidation. Mechanisms of Ageing and Development, 95, 81–99. [CrossRef] [PubMed] [Google Scholar]
  61. Singh R, Barden A, Mori T, Beilin L. 2001. Advanced glycation end-products: a review. Diabetologia, 44, 129–146. [CrossRef] [PubMed] [Google Scholar]
  62. Uribarri J, Cai W, Sandu O, Peppa M, Goldberg T, Vlassara H. 2005. Diet-derived advanced glycation end products are major contributors to the body’s AGE pool and induce inflammation in healthy subjects. Annals of the New York Academy of Sciences, 1043, 461–466. [CrossRef] [PubMed] [Google Scholar]
  63. Uribarri J, Cai W, Peppa M, Goodman S, Ferrucci L, Striker G, Vlassara H. 2007. Circulating glycotoxins and dietary advanced glycation endproducts: two links to inflammatory response, oxidative stress, and aging. Journal of Gerontology Series A: Biological Sciences and Medical Sciences, 62, 427–433. [CrossRef] [Google Scholar]
  64. Uribarri J, Woodruff S, Goodman S, Cai W, Chen X, Pyzik R, Yong A, Striker GE, Vlassara H. 2010. Advanced glycation end products in foods and a practical guide to their reduction in the diet. Journal of American Dietetic Association, 110(911–916), e12. [CrossRef] [Google Scholar]
  65. Vafa M, Maiga B, Israelsson E, Dolo A, Doumbo OK, Troye-Blomberg M. 2009. Impact of the IL-4 -590 C/T transition on the levels of Plasmodium falciparum specific IgE, IgG, IgG subclasses and total IgE in two sympatric ethnic groups living in Mali. Microbes and Infection, 11, 779–784. [CrossRef] [Google Scholar]
  66. Van de Pavert SA, Ferreira M, Domingues RG, Ribeiro H, Molenaar R, Moreira-Santos L, Almeida FF, Ibiza S, Barbosa I, Goverse G, Labão-Almeida C, Godinho-Silva C, Konijn T, Schooneman D, O’Toole T, Mizee MR, Habani Y, Haak E, Santori FR, Littman DR, Schulte-Merker S, Dzierzak E, Simas JP, Mebius RE, Veiga-Fernandes H. 2014. Maternal retinoids control type 3 innate lymphoid cells and set the offspring immunity. Nature, 508, 123–127. [CrossRef] [PubMed] [Google Scholar]
  67. Van Zoelen MAD, Schmidt AM, Florquin S, Meijers JC, de Beer R, de Vos AF, Nawroth PP, Bierhaus A, van der Poll T. 2009. Receptor for advanced glycation end products facilitates host defense during Escherichia coli-induced abdominal sepsis in mice. Journal of Infectious Diseases, 200, 765–773. [CrossRef] [Google Scholar]
  68. Van Zoelen MAD, van der Sluijs KF, Achouiti A, Florquin S, Braun-Pater JM, Yang H, Nawroth PP, Tracey KJ, Bierhaus A, van der Poll T. 2009. Receptor for advanced glycation end products is detrimental during influenza A virus pneumonia. Virology, 391, 265–273. [CrossRef] [PubMed] [Google Scholar]
  69. Van Zoelen MAD, Achouiti A, Schmidt AM, Yang H, Florquin S, Tracey KJ, van der Poll T. 2010. Ligands of the receptor for advanced glycation end products, including high-mobility group box 1, limit bacterial dissemination during Escherichia coli peritonitis. Critical Care Medicine, 38, 1414–1422. [CrossRef] [PubMed] [Google Scholar]
  70. Van Zoelen MAD, Achouiti A, van der Poll T. 2011. RAGE during infectious diseases. Frontiers in Bioscience. Scholar Edition, 3, 1119–1132. [Google Scholar]
  71. Van Zoelen MAD, Achouiti A, van der Poll T. 2011. The role of receptor for advanced glycation endproducts (RAGE) in infection. Critical Care, 15, 208. [CrossRef] [Google Scholar]
  72. Veldhoen M, Ferreira C. 2015. Influence of nutrient-derived metabolites on lymphocyte immunity. Nature Medicine, 21, 709–718. [CrossRef] [PubMed] [Google Scholar]
  73. Veldhoen M, Hirota K, Westendorf AM, Buer J, Dumoutier L, Renauld JC, Stockinger B. 2008. The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins. Nature, 453, 106–109. [CrossRef] [PubMed] [Google Scholar]
  74. Verma R, Khanna P, Chawla S. 2013. Malaria vaccine can prevent millions of deaths in the world. Human Vaccines and Immunotherapeutics, 9, 1268–1271. [CrossRef] [Google Scholar]
  75. Vlassara H, Cai W, Goodman S, Pyzik R, Yong A, Chen X, Zhu L, Neade T, Beeri M, Silverman JM, Ferrucci L, Tansman L, Striker GE, Uribarri J. 2009. Protection against loss of innate defenses in adulthood by low advanced glycation end products (AGE) intake: role of the antiinflammatory AGE receptor-1. Journal of Clinical Endocrinology and Metabolism, 94, 4483–4491. [CrossRef] [Google Scholar]
  76. World Health Organization, Global Malaria Programme, World Health Organization. 2014. World Malaria Report 2014. [Google Scholar]
  77. Xu Q, Xue F, Yuan B, Zhang L, Li J, He Z. 2012. The interaction between RAGE gene polymorphisms and HPV infection in determining the susceptibility of cervical cancer in a Chinese population. Cancer Biomarkers: Section A of Disease Markers, 11, 147–153. [Google Scholar]
  78. Yan SF, Ramasamy R, Schmidt AM. 2009. Receptor for AGE (RAGE) and its ligands—cast into leading roles in diabetes and the inflammatory response. Journal of Molecular Medicine, 87, 235–247. [CrossRef] [PubMed] [Google Scholar]
  79. Yan SF, Ramasamy R, Schmidt AM. 2010. Soluble RAGE: therapy and biomarker in unraveling the RAGE axis in chronic disease and aging. Biochemical Pharmacology, 79, 1379–1386. [CrossRef] [PubMed] [Google Scholar]
  80. Yan SF, Ramasamy R, Schmidt AM. 2010. The RAGE axis: a fundamental mechanism signaling danger to the vulnerable vasculature. Circulation Research, 106, 842–853. [CrossRef] [MathSciNet] [PubMed] [Google Scholar]
  81. Yildiz F. 2009. Advances in Food Biochemistry. CRC Press: Boca Raton. [CrossRef] [Google Scholar]
  82. Yilmaz B, Portugal S, Tran TM, Gozzelino R, Ramos S, Gomes J, Regalado A, Cowan PJ, d’Apice AJF, Chong AS, Doumbo OK, Traore B, Crompton PD, Silveira H, Soares MP. 2014. Gut microbiota elicits a protective immune response against malaria transmission. Cell, 159, 1277–1289. [CrossRef] [PubMed] [Google Scholar]
  83. Yin Y, Liu W, Ji G, Dai Y. 2013. The essential role of p38 MAPK in mediating the interplay of oxLDL and IL-10 in regulating endothelial cell apoptosis. European Journal of Cell Biology, 92, 150–159. [CrossRef] [PubMed] [Google Scholar]
  84. Zhang G, Skorokhod OA, Khoo SK, Aguilar R, Wiertsema S, Nhabomba AJ, Marrocco T, McNamara-Smith M, Manaca M, Barbosa A, Quintó L, Hayden CM, Goldblatt J, Guinovart C, Alonso PL, Dobaño C, Schwarzer E, LeSouëf PN. 2014. Plasma advanced oxidative protein products are associated with anti-oxidative stress pathway genes and malaria in a longitudinal cohort. Malaria Journal, 13, 134. [CrossRef] [PubMed] [Google Scholar]
  85. Zhang W, Lan Y, Huang Q, Hua Z. 2013. Galangin induces B16F10 melanoma cell apoptosis via mitochondrial pathway and sustained activation of p38 MAPK. Cytotechnology, 65, 447–455. [CrossRef] [PubMed] [Google Scholar]
  86. Zheng F, Tang Q, Wu J, Zhao S, Liang Z, Li L, Wu W, Hann S. 2014. p38α MAPK-mediated induction and interaction of FOXO3a and p53 contribute to the inhibited-growth and induced-apoptosis of human lung adenocarcinoma cells by berberine. Journal of Experimental and Clinical Cancer Research: CR, 33, 36. [CrossRef] [Google Scholar]
  87. Zimmerman PA, Ferreira MU, Howes RE, Mercereau-Puijalon O. 2013. Red blood cell polymorphism and susceptibility to Plasmodium vivax. Advances in Parasitology, 81, 27–76. [CrossRef] [PubMed] [Google Scholar]

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