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Table 2
Toxoplasma seroprevalence in pregnant women and demographic characteristics associated with seropositivity, Lyon, 2017–2023 (n = 71,922).
| Variables | n | % | Seroprev., % | Crude PR | 95% CI | p-value | aPR | 95% CI | p-value |
|---|---|---|---|---|---|---|---|---|---|
| Age (years) | |||||||||
| <25 | 6,530 | 9.1 | 19.1 | 0.74 | 0.69–0.79 | <0.001 | 0.66 | 0.62–0.71 | <0.001 |
| 25–29 | 19,231 | 26.7 | 18.9 | 0.73 | 0.70–0.77 | <0.001 | 0.71 | 0.68–0.74 | <0.001 |
| 30–34 | 27,228 | 37.9 | 24.1 | Ref. | Ref. | Ref. | Ref. | Ref. | Ref. |
| 35–39 | 15,149 | 21.1 | 30.4 | 1.37 | 1.31–1.44 | <0.001 | 1.33 | 1.27–1.39 | <0.001 |
| ≥40 | 3,784 | 5.3 | 38.0 | 1.93 | 1.79–2.07 | <0.001 | 1.78 | 1.65–1.91 | <0.001 |
| Total | 71,922 | 100.0 | NA | NA | NA | NA | NA | NA | NA |
| Place of residence | |||||||||
| Urban area | 63,244 | 88.0 | 24.9 | Ref. | Ref. | Ref. | Ref. | Ref. | Ref. |
| Rural area | 8,625 | 12.0 | 19.8 | 0.75 | 0.71–0.79 | <0.001 | 0.87 | 0.82–0.92 | <0.001 |
| Total | 71,869 | 100.0 | NA | NA | NA | NA | NA | NA | NA |
| Parity | |||||||||
| First pregnancy | 32,751 | 45.5 | 21.2 | Ref. | Ref. | Ref. | Ref. | Ref. | Ref. |
| ≥2 | 39,162 | 54.5 | 26.9 | 1.37 | 1.33–1.42 | <0.001 | 1.08 | 1.04–1.12 | <0.001 |
| Total | 71,913 | 100.0 | NA | NA | NA | NA | NA | NA | NA |
| Country/WHO Region of birth | |||||||||
| France | 51,514 | 72.5 | 20.6 | Ref. | Ref. | Ref. | Ref. | Ref. | Ref. |
| African Region (AFR) | 10,282 | 14.5 | 39.9 | 2.55 | 2.44–2.67 | <0.001 | 2.54 | 2.43–2.66 | <0.001 |
| Region of the Americas (AMR) | 659 | 0.9 | 21.9 | 1.08 | 0.89–1.29 | 0.4 | 0.98 | 0.81–1.18 | 0.859 |
| Eastern Mediterranean Region (EMR) | 3,844 | 5.4 | 33.2 | 1.91 | 1.78–2.05 | <0.001 | 1.85 | 1.72–1.99 | <0.001 |
| European Region (EUR) | 3,913 | 5.5 | 24.9 | 1.27 | 1.18–1.37 | <0.001 | 1.30 | 1.21–1.41 | <0.001 |
| South-East Asian Region (SEAR) | 201 | 0.3 | 19.4 | 0.93 | 0.64–1.30 | 0.7 | 0.89 | 0.616–1.25 | 0.511 |
| Western Pacific Region (WPR) | 616 | 0.9 | 9.1 | 0.38 | 0.29–0.50 | <0.001 | 0.35 | 0.26–0.46 | <0.001 |
| Total | 71,029 | 100.0 | NA | NA | NA | NA | NA | NA | NA |
Seroprev.: seroprevalence; Crude PR: crude prevalence ratio; aPR: adjusted prevalence ratio; Bold p-values indicate statistical significance
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