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Table 2

Toxoplasma seroprevalence in pregnant women and demographic characteristics associated with seropositivity, Lyon, 2017–2023 (n = 71,922).

Variables n % Seroprev., % Crude PR 95% CI p-value aPR 95% CI p-value
Age (years)
 <25 6,530 9.1 19.1 0.74 0.69–0.79 <0.001 0.66 0.62–0.71 <0.001
 25–29 19,231 26.7 18.9 0.73 0.70–0.77 <0.001 0.71 0.68–0.74 <0.001
 30–34 27,228 37.9 24.1 Ref. Ref. Ref. Ref. Ref. Ref.
 35–39 15,149 21.1 30.4 1.37 1.31–1.44 <0.001 1.33 1.27–1.39 <0.001
 ≥40 3,784 5.3 38.0 1.93 1.79–2.07 <0.001 1.78 1.65–1.91 <0.001
 Total 71,922 100.0 NA NA NA NA NA NA NA
Place of residence
 Urban area 63,244 88.0 24.9 Ref. Ref. Ref. Ref. Ref. Ref.
 Rural area 8,625 12.0 19.8 0.75 0.71–0.79 <0.001 0.87 0.82–0.92 <0.001
 Total 71,869 100.0 NA NA NA NA NA NA NA
Parity
 First pregnancy 32,751 45.5 21.2 Ref. Ref. Ref. Ref. Ref. Ref.
 ≥2 39,162 54.5 26.9 1.37 1.33–1.42 <0.001 1.08 1.04–1.12 <0.001
 Total 71,913 100.0 NA NA NA NA NA NA NA
Country/WHO Region of birth
 France 51,514 72.5 20.6 Ref. Ref. Ref. Ref. Ref. Ref.
 African Region (AFR) 10,282 14.5 39.9 2.55 2.44–2.67 <0.001 2.54 2.43–2.66 <0.001
 Region of the Americas (AMR) 659 0.9 21.9 1.08 0.89–1.29 0.4 0.98 0.81–1.18 0.859
 Eastern Mediterranean Region (EMR) 3,844 5.4 33.2 1.91 1.78–2.05 <0.001 1.85 1.72–1.99 <0.001
 European Region (EUR) 3,913 5.5 24.9 1.27 1.18–1.37 <0.001 1.30 1.21–1.41 <0.001
 South-East Asian Region (SEAR) 201 0.3 19.4 0.93 0.64–1.30 0.7 0.89 0.616–1.25 0.511
 Western Pacific Region (WPR) 616 0.9 9.1 0.38 0.29–0.50 <0.001 0.35 0.26–0.46 <0.001
 Total 71,029 100.0 NA NA NA NA NA NA NA

Seroprev.: seroprevalence; Crude PR: crude prevalence ratio; aPR: adjusted prevalence ratio; Bold p-values indicate statistical significance

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