Table 1
Summary of all the results from each evaluation applied to the top 15 Nippostrongylus brasiliensis candidates ranked by total score. Sc_Nam: score obtained from the homology analysis against Necator americanus; Sc_Mammal: score obtained from the homology analysis against Homo sapiens and Mus musculus; Sc_locat: score obtained from the extracellular localization analysis, Sc_protease: score obtained from the functional analysis; Sc_Ace: score obtained from the homology with expression of gut proteins in Ancylostoma ceylanicum; Sc_Bepit: score obtained after B-cell epitope prediction analysis; Sc_MHCII: score obtained after MHC-II prediction analysis; Score: total score obtained for each protein.
| Protein | Sc_Nam | Sc_Mammal | Sc_locat | Sc_protease | Sc_Ace | Sc_Bepit | Sc_MHCII | Score |
|---|---|---|---|---|---|---|---|---|
| NBR_0000584601 | 1 | 5 | 10 | 5 | 0 | 5 | 0 | 26 |
| NBR_0000892601 | 5 | 1 | 10 | 5 | 1 | 2 | 1 | 25 |
| NBR_0001337201 | 5 | 3 | 10 | 0 | 0 | 5 | 2 | 25 |
| NBR_0000752401 | 3 | 5 | 5 | 0 | 5 | 5 | 1 | 24 |
| NBR_0000897601 | 3 | 5 | 10 | 0 | 3 | 3 | 0 | 24 |
| NBR_0001090101 | 5 | 3 | 5 | 5 | 1 | 3 | 2 | 24 |
| NBR_0001394301 | 5 | 3 | 10 | 0 | 1 | 5 | 0 | 24 |
| NBR_0000014101 | 3 | 5 | 10 | 0 | 1 | 4 | 0 | 23 |
| NBR_0000612601 | 5 | 5 | 3 | 0 | 1 | 5 | 4 | 23 |
| NBR_0000723701 | 3 | 4 | 5 | 1 | 1 | 5 | 4 | 23 |
| NBR_0000844701 | 4 | 5 | 10 | 0 | 1 | 3 | 0 | 23 |
| NBR_0000992501 | 3 | 4 | 10 | 1 | 1 | 2 | 2 | 23 |
| NBR_0000823901 | 2 | 5 | 3 | 5 | 1 | 5 | 1 | 22 |
| NBR_0000928101 | 4 | 5 | 3 | 0 | 5 | 5 | 0 | 22 |
| NBR_0001356301 | 1 | 5 | 10 | 0 | 1 | 5 | 0 | 22 |
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