Open Access
Table 5
Comparison of sensitivity and specificity of Toxo-ISAGA IgM® and ELISA techniques (Architect/Alinity®, Vidas Toxo IgM®, Platelia Toxo IgM®) on 1,206 neonate sera.
| Assay (number of sera) | Sensitivity % [95% CI] | Specificity % [95% CI] | p value |
|---|---|---|---|
| Toxo-ISAGA IgM® (n = 1206) | 63.1% [59.5–66.5] | 98.4% [96.8–99.2] | Reference |
| Architect or Alinity® (n = 285) | 48.6% [41.8–55.3] | 100% [92.2–100] | <0.0001 |
| Vidas Toxo IgM® (n = 177) | 17.5% [10.0–28.6] | 100% [96.7–100] | <0.0001 |
| Platelia Toxo IgM® (n = 344) | 64.6% [57.6–71.0] | 95.4% [90.8–97.7] | 0.2752 |
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