Open Access
Table 2
Comparison of sensitivity, specificity, and accuracy of Toxo-ISAGA IgM® and ELISA techniques (Liaison Toxo IgM®, Architect/Alinity®, Vidas Toxo IgM®, Platelia Toxo IgM®) on the same groups of adult sera.
| Assay (number of sera) | Sensitivity % [95% CI] |
Specificity % [95% CI] |
Accuracy % |
P value |
|||||
|---|---|---|---|---|---|---|---|---|---|
| Borderline values considered positive | Borderline values considered negative | Borderline values considered positive | Borderline values considered negative | Borderline values considered positive | Borderline values considered negative | Borderline values considered positive | Borderline values considered negative | ||
| Toxo-ISAGA IgM® (n = 884) | 97.9% [92.7–99.6] | 94.8% [88.4–97.8] | 90.1% [87.8–92.0] | 78.7% [75.7–81.4] | 80.8% | 90.6% | |||
| Liaison Toxo IgM® (n = 884) | 90.6% [83.1–95.0] | 84.4% [75.8–90.3] | 95.2% [93.5–96.5] | 91.2% [89.0–93-0] | 91.2% | 94.0% | <0.0001 | <0.0001 | |
| Toxo-ISAGA IgM® (n = 413) | 100% [92.4–100] | 93.6% [82.8–97.8] | 70.2% [65.3–74.7] | 85.8% [81.8–89.0] | 73.6% | 86.7% | |||
| Architect/Alinity® (n = 413) | 95.7% [85.5–99.2] | 91.5% [80.0–96.6] | 60.4% [55.3–65.3] | 66.4% [61.4–71.0] | 64.4% | 69.3% | <0.0001 | <0.0001 | |
| Toxo-ISAGA IgM® (n = 78) | 100% [74.1–100] | 100% [74.1–100] | 55.2% [43.4–66.5] | 71.6% [59.9–81.0] | 61.5% | 75.6% | |||
| Vidas Toxo IgM® (n = 78) | 81.8% [52.3–96.8] | 63.6% [35.4–84.8] | 71.6% [59.9–81.0] | 76.1% [64.7–84.7] | 73.1% | 74.4% | 0.0012 | 0.0126 | |
| Toxo-ISAGA IgM® (n = 59) | 100% [82.4–100] | 100% [82.4–100] | 39.0% [25.7–54.3] | 43.9% [29.9–59.0] | 57.6% | 61.0% | |||
| Platelia Toxo IgM® (n = 59) | 94.4% [74.2–99.7] | 88.9% [67.2–98.0] | 24.4% [13.8–39.3] | 26.8% [15.7–41.9] | 45.8% | 45.8% | 0.1464 | 0.3068 | |
Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.
Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.
Initial download of the metrics may take a while.