Differential expression of key gene families involved in the pathogenesis of O. viverrini infection. Opisthorchis viverrini flukes were collected from diabetic (DM) and non-diabetic (NC) hamsters at day 21 (D21) and day 35 (D35). The log2 fold change in expression levels is presented for granulin, glutathione transferase, tetraspanins, thioredoxin, and the cathepsin family genes. Orange bars represent the comparison between D21-DM and D21-NC, while blue bars represent the comparison between D35-DM and D35-NC. ^* indicates genes with significant differential expression (DEGs).