Mean fold changes (n = 5) relative to control in the four different tot genes (TotA, TotC, TotM, TotX). Significant differences, resulting from Tukey post-hoc tests, are indicated with different letters. The symbol (*) indicates when mean values were different from the control. The treatment groups are from left to right: Acute 2 h, Acute 8 h, Chronic 2 h, Chronic 8 h, Infection 2 h, Infection 8 h, Infection × acute 2 h, Infection × acute 8 h, Infection × chronic 8 h.