Open Access
Table 1
Results of recombinant antigen-based immunochromatography tests (NIE, SsIR, and NIE-SsIR ICT kits) for detection of anti-Strongyloides IgG antibody in human serum samples.
| Conditions represented by sera | No. of sera tested | NIE ICT kit |
SsIR ICT kit |
NIE-SsIR ICT kit |
|---|---|---|---|---|
| No. positive2 | No. positive2 | No. positive2 | ||
| Group I | ||||
| Healthy controls | 40 | 0 | 0 | 0 |
| Group II | ||||
| Proven strongyloidiasis | 100 | 81 | 89 | 95 |
| Group III | ||||
| Giardiasis | 7 | 1 | 2 | 2 |
| Amoebiasis | 10 | 1 | 3 | 0 |
| Blastocystosis | 10 | 2 | 4 | 3 |
| Opisthorchiasis | 10 | 5 | 2 | 0 |
| Fascioliasis | 10 | 3 | 1 | 3 |
| Paragonimiasis | 10 | 2 | 1 | 0 |
| Taeniasis | 10 | 2 | 3 | 1 |
| Cysticercosis | 10 | 3 | 2 | 2 |
| Sparganosis | 7 | 3 | 2 | 3 |
| Hookworm infections | 10 | 4 | 4 | 1 |
| Ascariasis | 10 | 0 | 0 | 0 |
| Trichuriasis | 10 | 2 | 0 | 0 |
| Trichinellosis | 10 | 0 | 2 | 1 |
| Angiostrongyliasis | 10 | 1 | 3 | 2 |
| Gnathostomiasis | 10 | 0 | 2 | 0 |
| Capillariasis | 10 | 2 | 1 | 1 |
| Diagnostic values [95% CI1] | ||||
| Sensitivity (%) | 81.0 [71.9–88.2] | 89.0 [81.2–94.4] | 95.0 [88.7–98.4] | |
| Specificity (%) | 84.0 [78.1–88.9] | 83.5 [77.5–88.4] | 90.2 [85.1–94.0] | |
| Positive likelihood ratio | 5.07 [3.62–7.10] | 5.40 [3.90–7.46] | 9.70 [6.31–14.90] | |
| Negative likelihood ratio | 0.23 [0.15–0.34] | 0.13 [0.08–0.23] | 0.06 [0.02–0.13] | |
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