Parasite counts and efficacy.
|Parasite||Study/treatment groups||Number of positive cats/number of cats in group||Geometric mean parasite count (range)||Efficacy1 (%)||p-value2|
|Adult Toxocara cati||Study 1, induced infection (Tennessee, USA)|
|Placebo (control)3||10/10||29.5 (14–57)||100||<0.0001|
|Study 2, natural infection (Albania)|
|Placebo (control)||10/10||12.1 (2–32)||98.8||<0.0001|
|Dipylidium caninum||Study 3, induced infection (South Africa)|
|Placebo (control)||7/8||28.9 (8–267)||98.0||0.0018|
|Study 4, natural infection (Albania)|
|Placebo (control)||9/10||23.1 (3–143)||98.3||0.0001|
|Study 5, natural infection (Mexico)|
|Placebo (control)||7/10||5.6 (1–370)||93.2||0.0052|
Percent efficacy = 100[(C − T)/C], where C was the geometric mean among placebo controls and T was the geometric mean among the treated animals.
Two-sided probability value from analysis of variance on log-counts of the treated group and the placebo control group.
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