Table 2

Efficacy of the novel formulation against induced E. multilocularis infections in cats.

E. multilocularis counts
Efficacyc (%) p-valued
Placebo group
Novel formulation group
NI/NGa GMb (range) NI/NGa GMb (range)
Study #1 5/10 8.9 (0–1025) 0/10 0.0 (0) 100.0 0.0123
Study #2 8/10 28.8 (0–345) 0/10 0.0 (0) 100.0 0.0002

NI/NG: number of cats infected/number of cats in the group.


GM = geometric mean.


Percent efficacy = ([C – T]/C) × 100, where T and C were geometric means of the placebo and the novel formulation groups, respectively.


p-value = two-sided probability value from analysis of variance on log-counts of placebo and novel formulation groups.

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