Ixodes scapularis studies: mean live tick counts per group and efficacy results
|Study||n||Arithmetic means (AM) of live ticks and % efficacy1 on indicated days|
|I. scapularis #1||Day 2||Day 9||Day 16||Day 23||Day 32|
|I. scapularis #2||Day 2||Day 9||Day 16||Day 22||Day 32|
Note: p-values5 for comparison of the untreated and treated groups = <0.0001 at all time-points.
n = number of cats per group.
The I. scapularis counts were analyzed using SAS Version 9.4. The logarithm of the (count + 1) was analyzed at each study day separately using the MIXED procedure with treatment group used as a fixed effect and blocks used as a random effect.
Treated group = Novel formulation administered topically once on Day 0 at 0.12 mL/kg, providing 1.4 mg/kg esafoxolaner, 10.0 mg/kg praziquantel and 0.5 mg/kg eprinomectin
Percent efficacy = [(C – T)/C] × 100, where C and T are the arithmetic means of the control and treated groups, respectively.
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