Efficacy of a novel topical combination of esafoxolaner, eprinomectin and praziquantel against Ixodes ricinus and Ixodes scapularis in cats

Special Issue – NexGard^® Combo (esafoxolaner, eprinomectin, praziquantel): A new endectocide spot-on formulation for cats. Invited Editor: Frédéric Beugnet

Open Access

Table 1

Regulatory context, location, timing and animals by study.

Study #	Regulatory status	Test site location	Date of experimental phase	Animals¹
Study #	Regulatory status	Test site location	Date of experimental phase	Number and sex	Age (months)	Bodyweight (kg)
I. ricinus #1	GCP	Germany, EU	Nov–Dec 2015	6 male, 6 female	16–34	2.6–5.3
I. ricinus #2	Exploratory	Germany, EU	Jul–Aug 2016	8 male, 8 female	10–25	2.6–5.8
I. ricinus #3	GCP	France, EU	May–Jul 2017	10 male, 10 female	6–8	2.7–5.7
I. scapularis #1	GCP	Missouri, USA	Jul–Sep 2017	8 male, 12 female	20–59	3.0–6.2
I. scapularis #2	GCP	Georgia, USA	Jan–Feb 2018	11 male, 9 female	8–12	2.2–5.3

All cats were Domestic Long/Short-Hair, healthy and purpose-bred.

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