Table 2
Study schedules.
| Study | Day 0 | Day 2 | Day 7 | Day 14 | Day 21 | Day 30 | Day 60 | Day 90 |
|---|---|---|---|---|---|---|---|---|
| USA (sentinelsa) | RC, T | – | – | – | – | RC, T | RC, T | RC |
| EU (sentinelsb) | RC, T | – | RC | RC | RC | RC | – | – |
| Japan (all cats) | isC, T | RC | – | – | – | RC | – | – |
| Australia (all cats) | RC, T | – | – | – | – | RC | – | – |
RC = flea removal and count; T = Treatment; isC = in situ flea thumb count (without flea removal).
In the USA, non-sentinel cats were only presented on Day 0 and Day 90 for physical examination and cutaneous assessment, and were treated at home by the owners on Days 30 and 60.
In the EU, non-sentinel cats were only presented on Day 0 and Day 30 for physical examination and cutaneous assessment.
Physical examinations for tolerance evaluations were performed at all visits (except in Australia).
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