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Research Article

Table 4

Average proportions of live fed sandflies and insecticidal efficacy at 1, 48 and 72 h post-exposure.

Day Hours post-exposure Average proportion of live fed sandflies ± 95% CI
Insecticidal efficacy (%) p-value**
Control group Afoxolaner group
1 1 h 100* 100*
48 h 66.7 ± 13.6 0* 100% p < 0.0027
72 h 56.5 ± 13.1 0* 100% p < 0.0027
14 1 h 96.7 ± 2.5 94.6 ± 6.0
48 h 50.7 ± 213.6 2.1 ± 1.9 95.9% p < 0.0047
72 h 47.5 ± 311.8 0* 100% p < 0.0047
28 1 h 99.1 ± 1.2 97.4 ± 2.1
48 h 73.7 ± 6.6 18.2 ± 21.2 75.2% p < 0.0129
72 h 60.5 ± 12.2 8.3 ± 14.4 86.3% p < 0.0043

Proportion of live fed sandflies per animal [%] = [(Live fed sandflies/Total fed sandflies) × 100].

Insecticidal efficacy (%) against sandflies = 100 × (PcPt)/Pc, where Pc = Arithmetic mean number of the proportion of live fed female sandflies in the control group; Pt = Arithmetic mean number of the proportion of live fed female sandflies in the treated group.

*

For all samples showing 0 or 100% live sandflies, there is no 95% CI.

**

p-value based on a Wilcoxon sum rank test on live fed female counts between groups at each time-point.

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