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Review Article

Table 1

P-type transport ATPases in the originally sequenced genomes of the Trypanosomatidae, 2005.

Protein Size (aa) Chromosome Accession Protein Size (aa) Chromosome Accession
P1B, Cu++, Co++ transport P3A, H+ transport
LM1 1163 33 Q4Q3X8 LM9 974 18 Q4QDN7
TB1 961 11 Q387C6 TB9 912 10 Q388Z3
TC1s/1p 954 39-S, 39-P Q4DIX9, Q4D866 TC9s 219 (p) 40-S Q4CP01
TC9p 484 (p) 40-P Q4CNY1
P2A, Ca++ transport (SERCA)
LM2 1023 4 Q95Z93 LM10 952 4 O97198
TB2 1011 5 Q57Z55 TB10 Absent
TC2s 1006 21-S Q4DIM7 TC10s 898 8-S Q4DE37
P2B, Ca++ transport (PMCA) P4, aminophospholipid translocation
LM3 1104 7 Q4QIM8 LM11 1279 30 Q4Q767
TB3 1080 8 D6XMU9 TB11 1196 6 Q584Z5
TC3s/3p 1101, 1103 19-S, 19-P Q4E3S6, Q4DSJ2 TC11s/11p 1217 32-S, 32-P Q4DXI9, Q4DT76
LM4 1119 7 Q4QIM6 LM12 1491 34 Q4Q2T2
TB4 1106 8 Q57VN6 TB12 Absent
TB4b 1102 8 Q57VN8 TC12s 1259 34-S Q4DPV1
TC4 Absent
LM5 1194 33 Q4Q490 LM13 1157 34 Q4Q2M2
TB5 1100 10 Q389H9 TB13 1080 4 Q581T0
TC5p 1060 37-P Q4DPA3 TC13s 1143 34-S Q4DSF6
LM6 1051 17 Q4QED4 LM14 2525 9 Q4QHT5
TB6 Absent TB14 1569 11 Q382N5
TC6 Absent TC14p 1356 (p) 41-P Q4D911
P2D, Na+ transport
LM7 1109 35 E9AF31 LM15 1097 13 Q4QG01
TB7 1041 9 Q38CW7 TB15 1128 11 Q386H6
TC7s/7p 1039 39-S 39-P Q4DST4, Q4DU38 TC15s/15p 1099 14-S, 14-P Q4D434, Q4DGD2
P3A, H+ transport P5A, unknown ion specificity
LM8 974 18 Q4QDN8 LM16 1244 7 Q4QII2
TB8 920 10 Q388Z2 TB16 1261 8 Q57YG5
TC8s 259 (p) 40-S Q4CRY5 TC16p 1246 19-P Q4DK98
TC8p 256 (p) 40-P Q4DL30

Notes. LM, L. major (strain Friedlin); TB, Trypanosoma brucei brucei (TREU927, strain 927/4 GUTat10.1); TC, Trypanosoma cruzi (strain CL Brener); T. cruzi chromosome designation “S”, Esmeraldo like; T. cruzi chromosome designation “P”, Non-Esmeraldo-like; (p), partial open reading frame. Accession numbers are from the UniProtKB (http://www.uniprot.org) and TriTrypDB (http://tritrypdb.org/tritrypdb/) databases.

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