Table 1
P-type transport ATPases in the originally sequenced genomes of the Trypanosomatidae, 2005.
| Protein | Size (aa) | Chromosome | Accession | Protein | Size (aa) | Chromosome | Accession |
|---|---|---|---|---|---|---|---|
| P1B, Cu++, Co++ transport | P3A, H+ transport | ||||||
| LM1 | 1163 | 33 | Q4Q3X8 | LM9 | 974 | 18 | Q4QDN7 |
| TB1 | 961 | 11 | Q387C6 | TB9 | 912 | 10 | Q388Z3 |
| TC1s/1p | 954 | 39-S, 39-P | Q4DIX9, Q4D866 | TC9s | 219 (p) | 40-S | Q4CP01 |
| TC9p | 484 (p) | 40-P | Q4CNY1 | ||||
| P2A, Ca++ transport (SERCA) | |||||||
| LM2 | 1023 | 4 | Q95Z93 | LM10 | 952 | 4 | O97198 |
| TB2 | 1011 | 5 | Q57Z55 | TB10 | Absent | ||
| TC2s | 1006 | 21-S | Q4DIM7 | TC10s | 898 | 8-S | Q4DE37 |
| P2B, Ca++ transport (PMCA) | P4, aminophospholipid translocation | ||||||
| LM3 | 1104 | 7 | Q4QIM8 | LM11 | 1279 | 30 | Q4Q767 |
| TB3 | 1080 | 8 | D6XMU9 | TB11 | 1196 | 6 | Q584Z5 |
| TC3s/3p | 1101, 1103 | 19-S, 19-P | Q4E3S6, Q4DSJ2 | TC11s/11p | 1217 | 32-S, 32-P | Q4DXI9, Q4DT76 |
| LM4 | 1119 | 7 | Q4QIM6 | LM12 | 1491 | 34 | Q4Q2T2 |
| TB4 | 1106 | 8 | Q57VN6 | TB12 | Absent | ||
| TB4b | 1102 | 8 | Q57VN8 | TC12s | 1259 | 34-S | Q4DPV1 |
| TC4 | Absent | ||||||
| LM5 | 1194 | 33 | Q4Q490 | LM13 | 1157 | 34 | Q4Q2M2 |
| TB5 | 1100 | 10 | Q389H9 | TB13 | 1080 | 4 | Q581T0 |
| TC5p | 1060 | 37-P | Q4DPA3 | TC13s | 1143 | 34-S | Q4DSF6 |
| LM6 | 1051 | 17 | Q4QED4 | LM14 | 2525 | 9 | Q4QHT5 |
| TB6 | Absent | TB14 | 1569 | 11 | Q382N5 | ||
| TC6 | Absent | TC14p | 1356 (p) | 41-P | Q4D911 | ||
| P2D, Na+ transport | |||||||
| LM7 | 1109 | 35 | E9AF31 | LM15 | 1097 | 13 | Q4QG01 |
| TB7 | 1041 | 9 | Q38CW7 | TB15 | 1128 | 11 | Q386H6 |
| TC7s/7p | 1039 | 39-S 39-P | Q4DST4, Q4DU38 | TC15s/15p | 1099 | 14-S, 14-P | Q4D434, Q4DGD2 |
| P3A, H+ transport | P5A, unknown ion specificity | ||||||
| LM8 | 974 | 18 | Q4QDN8 | LM16 | 1244 | 7 | Q4QII2 |
| TB8 | 920 | 10 | Q388Z2 | TB16 | 1261 | 8 | Q57YG5 |
| TC8s | 259 (p) | 40-S | Q4CRY5 | TC16p | 1246 | 19-P | Q4DK98 |
| TC8p | 256 (p) | 40-P | Q4DL30 | ||||
Notes. LM, L. major (strain Friedlin); TB, Trypanosoma brucei brucei (TREU927, strain 927/4 GUTat10.1); TC, Trypanosoma cruzi (strain CL Brener); T. cruzi chromosome designation “S”, Esmeraldo like; T. cruzi chromosome designation “P”, Non-Esmeraldo-like; (p), partial open reading frame. Accession numbers are from the UniProtKB (http://www.uniprot.org) and TriTrypDB (http://tritrypdb.org/tritrypdb/) databases.
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