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IFN-γ and IL-10 mRNA expression within ZCL and SCL lesions. (A) Dot-plots show individual values of IFN-γ or IL-10 mRNA expression within ZCL (Δ) and SCL (▲) lesions. A horizontal bar indicates the median for each group. Results are expressed as the ratio between levels of cytokine mRNA in samples studied to those detected in normal skin. Differences between groups were considered statistically significant when p < 0.05. Nd: not detected. (B) Dot-plots show the ratio of IFN-γ/IL-10 mRNA levels calculated for each lesion. Horizontal bars indicate mean and the standard error of mean (SEM) for each group. (C) Correlation between IFN-γ or IL-10 mRNA levels and the age of lesions, their size, and the number of parasites they contain. Correlations between different variables were evaluated with the Spearman’s rank correlation test, r: correlation coefficient; p < 0.05 was considered statistically significant.
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