Table 3
Clinical and laboratory data of the 44 patients with cutaneous leishmaniasis studied. Intra- and inter-clusters division (numerical and categorical variables).
| Patient data | Cluster I (n = 7) | Cluster II (n = 24) | Cluster III (n = 13) |
|---|---|---|---|
| Gender | |||
| Female | 3 (42.9%) | 8 (33.3%) | 7 (53.8%) |
| Male | 4 (57.1%) | 16 (66.7%) | 6 (46.2%) |
| Age (mean)a | |||
| Mean ± SD | 33.29 ± 9.48 | 37.75 ± 12.16 | 28.31 ± 12.09 |
| Number of skin lesions | |||
| Median (min–max) | 1 (1–1) | 1 (1–15) | 2 (1–7) |
| Lesion location | |||
| Lower extremity | 2 (28.6%) | 15 (62.5%) | 6 (46.2%) |
| Upper limbsb | 5 (71.4%) | 3 (12.5%) | 5 (38.5%) |
| Head and cervical-facial | – | 3 (12.5%) | 3 (23.1%) |
| Torso | – | 7 (29.2%) | 2 (15.4%) |
| Lesion-evolution time (days) | |||
| Median (min–max) | 45 (30–90) | 60 (20–180) | 45 (30–270) |
| Number of treatmentsc | |||
| Median (min–max) | 1 (1–1) | 1.50 (1–4) | 2 (1–4) |
| MST | |||
| Reactor | 6 (100%) | 24 (100%) | 10 (90.9%) |
| Non-reactor | – | – | 1 (9.1%) |
| MST values (mm) | |||
| Median (min–max) | 21 (7–60) | 19 (7–57) | 12 (4–27) |
| ELISA | |||
| Reactor | 4 (66.7%) | 20 (90.9%) | 9 (75%) |
| Non-reactor | 2 (33.3%) | 2 (9.1%) | 3 (25%) |
| IIFd | |||
| Reactor | 2 (28.6%) | 14 (66.7%) | 10 (90.9%) |
| Non-reactor | 5 (71.4%) | 7 (33.3%) | 1 (9.1%) |
| Responsee | |||
| Responder | 7 (100%) | 12 (50%) | 4 (30.8%) |
| Non-responder | – | 12 (50%) | 9 (69.2%) |
| Region of Infectionf | |||
| Rio de Janeiro | 7 (100%) | 21 (87.5%) | 7 (53.8%) |
| Other states | – | 3 (12.5%) | 6 (46.2%) |
MST = Montenegro Skin Test; IIF = Indirect Immunofluorescence; RJ = Rio de Janeiro; OS = other states.
(Clusters I and II) p = 0.048 (Mann-Whitney U Test) and (clusters I and III) p = 0.011 (Mann-Whitney U Test).
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