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Table 3

Clinical and laboratory data of the 44 patients with cutaneous leishmaniasis studied. Intra- and inter-clusters division (numerical and categorical variables).

Patient data Cluster I (n = 7) Cluster II (n = 24) Cluster III (n = 13)
Gender      
  Female 3 (42.9%) 8 (33.3%) 7 (53.8%)
  Male 4 (57.1%) 16 (66.7%) 6 (46.2%)
Age (mean)a      
  Mean ± SD 33.29 ± 9.48 37.75 ± 12.16 28.31 ± 12.09
Number of skin lesions      
  Median (min–max) 1 (1–1) 1 (1–15) 2 (1–7)
Lesion location      
  Lower extremity 2 (28.6%) 15 (62.5%) 6 (46.2%)
  Upper limbsb 5 (71.4%) 3 (12.5%) 5 (38.5%)
  Head and cervical-facial 3 (12.5%) 3 (23.1%)
  Torso 7 (29.2%) 2 (15.4%)
Lesion-evolution time (days)      
  Median (min–max) 45 (30–90) 60 (20–180) 45 (30–270)
Number of treatmentsc      
  Median (min–max) 1 (1–1) 1.50 (1–4) 2 (1–4)
MST      
   Reactor 6 (100%) 24 (100%) 10 (90.9%)
  Non-reactor 1 (9.1%)
MST values (mm)      
  Median (min–max) 21 (7–60) 19 (7–57) 12 (4–27)
ELISA      
  Reactor 4 (66.7%) 20 (90.9%) 9 (75%)
  Non-reactor 2 (33.3%) 2 (9.1%) 3 (25%)
IIFd      
  Reactor 2 (28.6%) 14 (66.7%) 10 (90.9%)
   Non-reactor 5 (71.4%) 7 (33.3%) 1 (9.1%)
Responsee      
   Responder 7 (100%) 12 (50%) 4 (30.8%)
   Non-responder 12 (50%) 9 (69.2%)
Region of Infectionf      
   Rio de Janeiro 7 (100%) 21 (87.5%) 7 (53.8%)
   Other states 3 (12.5%) 6 (46.2%)

MST = Montenegro Skin Test; IIF = Indirect Immunofluorescence; RJ = Rio de Janeiro; OS = other states.

Mean ± SD = Mean and standard deviation.

p <  0.05 values are considered significant.

a

(Clusters II and III) p = 0.030 (T-Test).

b

(Clusters I and II) p = 0.006 (Fisher's Exact Test).

c

(Clusters I and II) p = 0.048 (Mann-Whitney U Test) and (clusters I and III) p = 0.011 (Mann-Whitney U Test).

d

(clusters I and III) p = 0.013 (Fisher's Exact Test).

e

(Clusters I and II) p = 0.026 (Fisher's Exact Test) and (clusters I and III) p = 0.005 (Fisher's Exact Test).

f

(Clusters II and III) p = 0.042 (Fisher's Exact Test).

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