Epitope analysis and protection by a ROP19 DNA vaccine against Toxoplasma gondii

Open Access

Table 3.

Cytokine production by splenocyte^a cultures from immunized BALB/c mice.

Group	Cytokine production (pg/mL)^b
	IFN-γ	IL-4	IL-10
PBS	54.44 ± 12.53	40.02 ± 9.18	39 ± 9.24
pEGFP-C1	54.30 ± 11.65	35.93 ± 8.95	41.73 ± 7.44
pEGFP-C1-ROP19	485.04 ± 64.559^*	40.12 ± 6.29	41.33 ± 4.94

Splenocytes from four mice per group two weeks after the final immunization.

Values for IFN-γ at 96 h, IL-4 at 24 h, and IL-10 at 72 h are expressed as mean ± SD.

Compared with PBS or pEGFP-C1 group, p < 0.05.

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