Table 1.
Cellular proliferation and cytokine production by splenocytes isolated from ROP17 DNA-immunized BALB/c mice and controls.
| Groups* | Cytokine production (pg/mL)**
|
Lymphocyte SI | |||
|---|---|---|---|---|---|
| IFN-γ | IL-2 | IL-4 | IL-10 | ||
| PBS | 41.29 ± 6.73a | 79.26 ± 5.35a | 78.84 ± 4.37a | 63.31 ± 5.13a | 1.02 ± 0.11a |
| p3×Flag-CMV-14 | 45.17 ± 6.93a | 81.14 ± 5.71a | 76.63 ± 5.15a | 66.457 ± 5.26a | 1.163 ± 0.12a |
| p3×Flag-CMV-14-ROP17 | 186.17 ± 11.47b | 158.41 ± 11.38b | 75.63 ± 2.73a | 70.25 ± 4.74a | 2.14 ± 0.23b |
Splenocytes were harvested from the mice 2 weeks after the final immunization. Results are presented as means ± the standard errors of three replicate experiments. Values for IFN-γ are for 96 h, values for IL-10 are for 72 h, and values for IL-2, IL-4 are for 24 h. Letter a indicates no statistical difference was observed (P > 0.05), and letter b means significant difference within each cytokine or lymphocyte SI group (compared with PBS or empty vector group, P < 0.05).
Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.
Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.
Initial download of the metrics may take a while.