Afoxolaner against fleas: immediate efficacy and resultant mortality after short exposure on dogs

Open Access

Table 1.

Immediate efficacy and induced mortality of afoxolaner against fleas after 2 h or 6 h of exposure on dogs.

	Immediate curative efficacy (Counts of live fleas removed from dogs^*)				Induced mortality (Counts of live fleas after 24 h in insectarium)
	Control group (n = 6)	Treated group (n = 10)			Control group (n = 6)	Treated group (n = 10)
Day −1 flea infestation	Control mean	Arithmetic mean	Geometric mean (Eff%)	p-value	Control mean	Arithmetic mean	Geometric mean (Eff%)	p-value
Day 0 + 2 h	75.5 (57–89)	74.5	70.5 (5.5)	>0.05	69.5 (47–86)	0.6	0.2 (99.7)	0.00138^*
Day 0 + 6 h	67.8 (40–88)	0	0 (100)	0.0138^*	62.7 (28–86)	/	/	/

The live fleas removed from dogs were put in the insectarium for 24 h. Induced mortality was evaluated as the survival of fleas measured in the insectarium after 24 h.

Day of treatment (Day 0). Time (in hours) after treatment (Day 0).

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