Table 1.
Results for ELISA tests rEm18 and Em2-Em18, and rEm18-ICT for AE (alveolar echinococcosis), CE and PE (cystic and polycystic echinococcosis), and other pathologies. Percentages of sensitivity, specificity, and the performance index for each test are shown.
| No. of seropositive samples for the three tests |
||||
|---|---|---|---|---|
| No. of samples | rEm18-ICT | rEm18-ELISA | Em2-Em18-ELISA | |
| AE | 30 | 27 | 26 | 29 |
| CE/PE | 16 | 5 | 4 | 5 |
| Other | 66 | 1 | 3 | 5 |
| Sensitivity, % | 90.0 | 86.7 | 96.7 | |
| (95% CI) | (78.4–96.1) | (74.4–93.9) | (85.8–99.4) | |
| Specificity, % | 92.7 | 91.5 | 87.8 | |
| (95% CI) | (88.4–94.9) | (87.0–94.1) | (83.8–88.8) | |
| Youden index | 0.83 | 0.78 | 0.85 | |
| (95% CI) | (0.67–0.91) | (0.61–0.88) | (0.70–0.88) | |
| Accuracy, % | 92.0 | 90.2 | 90.2 | |
| (95% CI) | (85.7–95.2) | (83.6–94.1) | (84.4–91.6) | |
| Positive likelihood ratio (LR+) | 12.3 | 10.2 | 7.9 | |
| (95% CI) | (6.7–18.9) | (5.7–16.0) | (5.3–8.9) | |
| Negative likelihood ratio (LR−) | 0.11 | 0.15 | 0.04 | |
| (95% CI) | (0.04–0.25) | (0.06–0.30) | (0.01–0.17) | |
| Diagnostic odds ratio | 114.0 | 69.6 | 208.8 | |
| (95% CI) | (27.7–461.2) | (19.4–248.5) | (31.5–1314.4) | |
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