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Table I.

Mean number and standard deviation of total circulating leukocytes (expressed in cells × 103/mm3) in the blood obtained 45, 55, 65 and 75 days after infection of BALB/c mice with the D8 or ME49 strains of Toxoplasma gondii.

Days after infection
Groups 45 55 65 75 45 55 65 75 45 55 65 75
Control Strain D8
ME49
Naive
Leukocytes (103/mm3) 5,31 ± 1,2 8,53 ± 2,7 9,0 ± 3,9 9,96 ± 4,2 5,83 ± 1,5 6,54 ± 1,3 7,23 ± 1,4 6,15 ± 1,2 8,16 ± 3,0 5,14 ± 1,0 7,69 ± 1,5 5,66 ± 0,5

Immunosuppressed Strain D8/Cy
ME49/Cy
Naive/Cy
Leukocytes (103/mm3) 2,03 ± 0,4* 2,88 ± 0,4* 3,16 ± 0,7* 2,98 ± 0,7* 3,17 ± 0,5* 2,81 ± 0,5* 2,75 ± 0,2* 2,59 ± 0,7* 4,56 ± 1,9* 3,15 ± 1,0* 3,42 ± 0,9* 3,17 ± 0,8*

Weekly immunosuppression with cyclophosphamide (Cy) began forty days after infection, until the end of the experiment. Control groups of non-immunosuppressed mice: D8, ME49 and Naive (without infection);

*

significant difference in relation to respective non-immunosuppressed control group (p < 0.05).

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