Fig. 4.
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Comparison of human and L. infantum GDP-MP models.
A. Superposition of human and L. infantum GDP-MP 3D models. Ribbon-tubes in green and orange represent the L. infantum and the human GDP-MPs, respectively. The F(V)EKP conserved motif is colored in yellow.
B. Position of the GDP-mannose in both human and L. infantum GDP-MPs. This figure represents the superposition of both human and L. infantum GDP-MPs including the substrate GDP-mannose (purple). The position of the GDP-mannose was determined by docking. Ribbon-tubes in green and orange represent the L. infantum and the human GDP-MPs, respectively. The F(V)EKP conserved motif is colored in yellow.
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