Issue |
Parasite
Volume 22, 2015
|
|
---|---|---|
Article Number | 35 | |
Number of page(s) | 5 | |
DOI | https://doi.org/10.1051/parasite/2015035 | |
Published online | 02 December 2015 |
Short Note
Effect of oral administration of Kudoa septempunctata genotype ST3 in adult BALB/c mice
Effet de l’administration orale de Kudoa septempunctata génotype ST3 à des souris BALB/c adultes
1
School of Medicine, Jeju National University, Jeju
63243, Republic of Korea
2
College of Veterinary Medicine, Jeju National University, Jeju
63243, Republic of Korea
3
Ocean and Fisheries Research Institute, Jeju Special Self-Governing Province, Pyoseon-myeon, Segwipo-si, Jeju
63629, Republic of Korea
* Corresponding author: shint@jejunu.ac.kr
a Co-corresponding authors: jyh4586@korea.kr; kbc1922@korea.kr
Received:
18
October
2015
Accepted:
24
November
2015
Kudoa septempunctata (Myxozoa: Multivalvulida) infects the muscles of olive flounder (Paralichthys olivaceus, Paralichthyidae) in the form of spores. To investigate the effect of K. septempunctata spores in mammals, adult BALB/c mice were fed with spores of K. septempunctata genotype ST3 (1.35 × 105 to 1.35 × 108 spores/mouse). After ingestion of spores, the mice remained clinically normal during the 24-h observation period. No spores were found in any tissue examined by histopathological screening. Quantitative PCR screening of the K. septempunctata 18S rDNA gene revealed that the K. septempunctata spores were detected only in the stool samples from the spore-fed groups. Collectively, these findings suggest that K. septempunctata spores are excreted in faeces and do not affect the gastrointestinal tract of adult mice.
Résumé
Kudoa septempunctata (Myxozoa: Multivalvulida) infecte les muscles du cardeau hirame (Paralichthys olivaceus, Paralichthyidae) sous la forme de spores. Pour étudier l’effet de l’ingestion de spores de K. septempunctata chez les mammifères, des souris BALB/c adultes ont été nourries avec des spores de génotype ST3 (1.35 × 105 à 1.35 × 108 spores/souris). Après ingestion de spores, les souris sont restées cliniquement normales pendant la période d’observation de 24 heures. Aucune spore n’a été trouvée dans les tissus examinés par dépistage histopathologique. Le criblage par PCR quantitative du gène d’ADNr 18S de K. septempunctata a révélé que les spores étaient détectées seulement dans les échantillons de selles des souris qui ont ingéré des spores. Collectivement, ces résultats suggèrent que les spores de K. septempunctata sont excrétées dans les fèces et n’affectent pas le tube digestif des souris adultes.
Key words: Kudoa septempunctata / ST3 genotype / Foodborne disease / Myxozoa / Olive flounder / Paralichthys olivaceus
© M. Ahn et al., published by EDP Sciences, 2015
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.
Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.
Initial download of the metrics may take a while.