Issue |
Parasite
Volume 20, 2013
|
|
---|---|---|
Article Number | 55 | |
Number of page(s) | 3 | |
DOI | https://doi.org/10.1051/parasite/2013056 | |
Published online | 19 December 2013 |
Short Note
Serum levels of brain-derived neurotrophic factor (BNDF) in multiple sclerosis patients with Trichuris suis ova therapy
Niveaux sériques du facteur neurotrophique dérivé du cerveau (BNDF) chez des patients atteints de sclérose en plaques sous thérapie par les œufs de Trichuris suis
1
Department of Neurology and Experimental Neurology, Charité Campus Mitte – Universitätsmedizin Berlin, Germany
2
Department of Psychiatry, Charité Campus Mitte – Universitätsmedizin Berlin, Germany
3
Competence Centre for Sleep Medicine, Charité Campus Benjamin Franklin – Universitätsmedizin Berlin, Germany
* Correspondence author: berit.rosche@charite.de
Received:
25
September
2013
Accepted:
10
December
2013
We previously analysed clinical and immunological parameters under Trichuris suis ova (TSO) therapy in four patients with secondary progressive multiple sclerosis. The serum Brain-derived neurotrophic factor (BDNF) levels of these four patients were assessed before, during and after therapy with TSO and showed significant decrease of BDNF during TSO therapy (p < 0.05).
Résumé
Nous avons précédemment analysé les paramètres cliniques et immunologiques sous thérapie par des œufs de Trichuris suis (TSO) chez quatre patients avec sclérose en plaques progressive secondaire. Les niveaux du facteur neurotrophique dérivé du cerveau (BNDF) chez ces quatre patients ont été mesurés avant, pendant et après la thérapie par TSO et ont montré une diminution significative du BNDF pendant la thérapie par TSO (p < 0.05).
Key words: Multiple sclerosis / Trichuris suis ova / Brain-derived neurotrophic factor / Neuroprotection
© B. Rosche et al., published by EDP Sciences, 2013
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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