Volume 15, Number 3, September 2008Xth European Multicolloquium of Parasitology (EMOP-10, Paris, August 24-28, 2008)
|Page(s)||349 - 358|
|Published online||15 September 2008|
Xth EMOP, August 2008
Enterocytozoon bieneusi in human and animals, focus on laboratory identification and molecular epidemiology
Unité INSERM 511, Faculté de Médecine
2 Université Paris VI, Faculté de Médecine Pierre et Marie Curie,
3 Assistance Publique Hôpitaux de Paris, Laboratoire de Parasitologie-Mycologie, Groupe Hospitalier Universitaire Pitié-Salpêtrière, Paris, France
* Correspondence: Marc Thellier, Assistance Publique Hôpitaux de Paris, Laboratoire de Parasitologie-Mycologie, CHU Pitié-Salpêtrière, 47, boulevard de l’Hôpital, 75013 Paris, France. Tel.: 33 (0)1 42 16 01 13 – Fax: 33 (0)1 42 16 01 65. E-mail: firstname.lastname@example.org
Human microsporidian infections have emerged following the onset of the AIDS pandemic. Microsporidia are unicellular eukaryotic parasites that form spores. They are an exceptionally diverse group of parasites that infect a wide range of eukaryotic cells in numerous invertebrate and vertebrate hosts. Of the 14 species newly described as pathogens in human, Enterocytozoon bieneusi, which causes gastrointestinal diseases, is the most common agent of human infections. In the past fifteen years, E. bieneusi was also identified in environmental sources, especially in surface water, as well as in wild, domestic and farm animals. These findings raised concerns for waterborne, foodborne and zoonotic transmission. Molecular analyses of the 243-bp internal Transcribed spacer-(ITS) of the rRNA gene have revealed a considerable genetic variation within E. bieneusi isolates of human and animal origins, supporting the potential for zoonotic transmission. The focus of this revue is to present and discuss recent advances in diagnosis and zoonotic potential of E. bieneusi infections.
Key words: Microsporidia / Enterocytozoon bieneusi / Internal Transcribed Spacer / diagnosis / molecular epidemiology / zoonotic
© PRINCEPS Editions, Paris, 2008, transferred to Société Française de Parasitologie
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