| Issue |
Parasite
Volume 15, Number 3, September 2008
Xth European Multicolloquium of Parasitology (EMOP-10, Paris, August 24-28, 2008)
|
|
|---|---|---|
| Page(s) | 206 - 210 | |
| DOI | https://doi.org/10.1051/parasite/2008153206 | |
| Published online | 15 September 2008 | |
Xth EMOP, August 2008
Toxoplasma gondii gene expression is under the control of regulatory pathways acting through chromatin structure
1
Laboratoire Adaptation et Pathogénie des Micro-organismes, Université Joseph Fourier Grenoble 1, BP 170, F-38042 Grenoble cedex 9, France
2
CNRS UMR 5163 – ATIP+ group
* Correspondence: Mohamed-Ali Hakimi. Tel.: 33 (0)4 76 63 74 69 – Fax: 33 (0)4 76 63 74 97. E-mail: Mohamed-Ali.Hakimi@ujf-grenoble.fr
The activity state of a gene is determined by a complex regulatory network of co-acting factors affecting the structure of the chromatin into which the gene is embedded. While significant changes of the transcriptome occur during cell differentiation in apicomplexan parasites, basic mechanisms controlling gene expression are still unknown. Recent studies support and expand the concept of the chromatin environment being key factor for the control of transcriptional activity in these lower eukaryotes organisms. Here, we review recent advances in the field of epigenetic gene regulation in Toxoplasma gondii, the model apicomplexan.
Key words: Apicomplexa / Toxoplasma gondii / chromatin / transcription / epigenetics
© PRINCEPS Editions, Paris, 2008, transferred to Société Française de Parasitologie
Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.
Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.
Initial download of the metrics may take a while.