Issue |
Parasite
Volume 11, Number 2, June 2004
|
|
---|---|---|
Page(s) | 189 - 199 | |
DOI | https://doi.org/10.1051/parasite/2004112189 | |
Published online | 22 August 2014 |
Mémoire
Regional genetic differentiation of Phlebotomus sergenti in three Moroccan foci of cutaneous leishmaniasis caused by Leishmania tropica
Différentiation génétique régionale de Phlebotomus sergenti dans trois foyers marocains de Leishmania tropica
1
Faculté de Médecine et Pharmacie, Université Hassan II Ain Chock, Casablanca, Morocco.
2
Molecular Systematics Laboratory, Department of Entomology, Natural History Museum, London, UK.
* Correspondence: P.D. Ready, Department of Entomology, Natural History Museum, London SW7 5BD, UK. Fax : 00 44 20 7942 5229. E-mail : P.Ready@nhm.ac.uk
** N. Guessous-Idrissi, Faculté de Médecine et Pharmacie, Université Hassan II Ain Chock, 19, Rue Tarik Ibnou Zaid, BP 9154, Casablanca, Morocco. Fax : 00 212 2 47 55 60 E-mail : ngi@fmp-uh2c.ac.ma
Received:
25
August
2003
Accepted:
30
October
2003
Phlebotomus sergenti was identified morphologically in samples from three Moroccan foci of leishmaniasis caused by Leishmania tropica in the provinces of Azilal, Essaouira and Taza. Three primary mitochondrial DNA lineages were identified, and they could be markers for regionally distributed cryptic species. Greater mitochondrial diversity in Azilal indicated that this central province could have been the origin of dispersal of P. sergenti or the zone of secondary contact. All except one of the 21 mitochondrial haplotypes showed a marked regional distribution, and this indicates that vector control would not always be followed by rapid, long-distance reinvasion. Only mitochondrial haplotype SER 18 was a putative marker for long-distance dispersal, for which there is no evidence of human assistance.
Résumé
Phlebotomus sergenti est identifié morphologiquement sur des spécimens originaires de trois foyers marocains à Leishmania tropica : Azilal, Essaouira et Taza. Trois lignées mitochondriales sont identifiées et pourraient être marqueurs d'espèces cryptiques avec une distribution régionale spécifique. La grande diversité mitochondriale trouvée à Azilal ferait de cette région l'origine de dispersion de P. sergenti ou la zone de contact secondaire des lignées vicariantes. Les distributions régionales des 21 haplotypes mitochondriaux, à l'exception de SER 18, possible marqueur d'une dispersion anthropogène, suggère que le contrôle vectoriel pourrait être efficace dans plusieurs localités, vu la lenteur et la faible portée de la recolonisation.
Key words: Leishmania tropica / Phlebotomus sergenti / mitochondrial lineages / host-parasite co-associations / phylogeography
Mots clés : Leishmania tropica / Phlebotomus sergenti / lignées mitochondriales / co-association hôte-parasite / phylogéographie
© PRINCEPS Editions, Paris, 2004, transferred to Société Française de Parasitologie
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