Xth ICT, August 2000

New aspects of clinical pathology and electro-physiological muscle disturbances in patients with history of trichinellosis

¹ Clinic of Parasitic and Tropical Diseases,
² Department of Pathophysiology,
³ Department of Clinical Pathomorphology, University of Medical Sciences, Przybyszewskiego 49, Poznan, Poland.

^* Correspondence : W. Kociecka, Clinic of Parasitic and Tropical Diseases, KMUMS, Przybyszewskiego 49, Poznan, Poland.

Abstract

Clinical studies performed in 44 patients, one, three, four, six or seven years after they had experienced trichinellosis demonstrated the persistence of various general and motor ailments in 88.7 % of the patients. The persisting for many years antibodies against E/S antigen of Trichinella in 86.4 % of examined patients seem to reflect chronic stimulation by the larvae which, as shown by parasitological and histopathological tests, survived longer and underwent gradual destruction in muscles. Bio-electric disturbances in muscles were most frequently of a mixed type, with prevalence of a neural type record. These observations illustrate a disturbed function of motor neurones and of impulse transmission at the myoneural junction in patients chronically infected with Trichinella.