Volume 1, Number 1S, March 19943rd CEC Filariasis Network Meeting (Lisbon -IHMT, 4-7 September 1993)
|Page(s)||S35 - S37|
|Published online||30 September 2014|
Parenteral administration of cytokines and drugs in rodent filariasis via osmotic pumps
Institut für Tropenmedizin, University of Tubingen, Germany.
2 Dept. of Pharmacology/Therapeutics, University of Nigeria, Enugu.
Changes in the cytokine production profile are supposed to be responsible for the different courses of parasitic infections. Therefore, a big effort is made to understand the roles of cytokines produced by different cells during parasitic infections. In the following text we describe first experiments with Interferon-γ done in a natural model for filariasis, the filariae Monanema martini in Lemniscomys striatus. For the application of this cytokine to the animals we implanted osmotic pumps, which deliver IFN-γ continuously.
Key words: Interferon-γ / osmotic pump / lemniscomys striatus / Monanema martini
© PRINCEPS Editions, Paris, 1994, transferred to Société Française de Parasitologie
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