| Issue |
Parasite
Volume 32, 2025
|
|
|---|---|---|
| Article Number | 32 | |
| Number of page(s) | 14 | |
| DOI | https://doi.org/10.1051/parasite/2025025 | |
| Published online | 03 June 2025 | |
Supplementary material
Supplementary Table 1: Data sheet containing all the results from the evaluation of the identity of the predicted proteomes of Nippostrongylus brasiliensis with Necator americanus. Nam_ident: Identity percentage with Necator americanus. Sc_Nam: score assigned to each of the N. brasiliensis proteins.
Supplementary Table 2: Data sheet containing all the results from the protein homology results between Nippostrongylus brasiliensis and mammalian species. Hsa_ident: Percentage of identity with Homo sapiens; Mmu_ident: percentage of identity with Mus musculus; Sc_Mammal: score assigned to each protein based on homology with other mammals; NF: not found.
Supplementary Table 3: Data sheet containing all the results from extracellular localization. Excreted secreted products (ES) or extracellular vesicles (EVs) secreted by adult or L3 larvae.
Supplementary Table 4: Data sheet containing all the results from the analysis of Nippostrongylus brasiliensis proteins with homologs expressed in the gut of the related hookworm Ancylostoma ceylanicum.
Supplementary Table 5: Data sheet containing all the results from the Pfam-based analysis that allocated Nippostrongylus brasiliensis proteins into four different groups according to the domain families to which they belonged.
Supplementary Table 6: Data sheet containing the results of the identification of linear B-cell epitopes and score given to each Nippostrongylus brasiliensis protein. Bepit_res: number of B-cell epitope residues; Bepit_res_perc: percentage of B-cell epitope residues compared to the total number of protein residues.
Supplementary Table 7: Data sheet containing the results of the identification of the presence of HLA class II epitopes with extended population coverage and score given to each Nippostrongylus brasiliensis protein.
Supplementary Table 8: Data sheet summarising all the results from each evaluation applied to the Nippostrongylus brasiliensis predicted proteins. Proteins are ranked by total score.
Supplementary Table 9: Data sheet containing a summarized and extended table of allergenicity and toxicity results of the top-15 candidates from Nippostrongylus brasiliensis.
Supplementary Table 10: Data sheet containing a summarized and extended table of the solubility and physicochemical properties of the top-15 candidates from Nippostrongylus brasiliensis.
Supplementary Table 11: Data sheet containing a summarized and an extended table of the allergenicity and toxicity results of the top-15 candidate homologs in Necator americanus.
Supplementary Table 12: Data sheet containing a summarized and extended table of the solubility and physicochemical properties of the top-15 candidate homologs in Necator americanus.
Access here© J. Sotillo et al., published by EDP Sciences, 2025
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