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Human Alveolar Echinococcosis—A Neglected Zoonotic Disease Requiring Urgent Attention
Ali Rostami, Britta Lundström-Stadelmann, Caroline F. Frey, Guido Beldi, Anja Lachenmayer, Bill C. H. Chang, Mohammad Mobin Norouzian, Andrew Hemphill and Robin B. Gasser International Journal of Molecular Sciences 26(6) 2784 (2025) https://doi.org/10.3390/ijms26062784
Host Proteins in Echinococcus multilocularis Metacestodes
Joachim Müller, Beatrice Zumkehr, Manfred Heller, Anne-Christine Uldry, Sophie Braga-Lagache and Britta Lundström-Stadelmann International Journal of Molecular Sciences 26(7) 3266 (2025) https://doi.org/10.3390/ijms26073266
Synthetic rEg.P29 Peptides Induce Protective Immune Responses Against Echinococcus granulosus in Mice
In vitro screening of the open-access Pandemic Response Box reveals ESI-09 as a compound with activity against Echinococcus multilocularis
Pascal Zumstein, Anissa Bartetzko, Marc Kaethner, Laura Vetter, Andrew Hemphill, Trix Zumkehr, Benoît Laleu, Matías Preza and Britta Lundström-Stadelmann International Journal for Parasitology: Drugs and Drug Resistance 29 100609 (2025) https://doi.org/10.1016/j.ijpddr.2025.100609
Efficacy and safety of pseudolaric acid B against Echinococcus multilocularis in vitro and in a murine infection model
Investigation of the threonine metabolism of Echinococcus multilocularis: The threonine dehydrogenase as a potential drug target in alveolar echinococcosis
Marc Kaethner, Pascal Zumstein, Joachim Müller, Matías Preza, Philipp Grossenbacher, Anissa Bartetzko, Laura Vetter, Martin Lochner, Stefan Schürch, Clement Regnault, Daniel Villalobos Ramírez and Britta Lundström-Stadelmann International Journal for Parasitology: Drugs and Drug Resistance 27 100581 (2025) https://doi.org/10.1016/j.ijpddr.2025.100581
Marc Kaethner, Pascal Zumstein, Matías Preza, Philipp Grossenbacher, Anissa Bartetzko, Martin Lochner, Stefan Schürch, Clement Regnault, Daniel Villalobos Ramírez and Britta Lundström-Stadelmann (2024) https://doi.org/10.1101/2024.07.27.605433
Receptor Tyrosine Kinase Signaling Involves Echinococcus–Host Intercommunication: A Potential Therapeutic Target in Hepatic Echinococcosis
Haijun Gao, Zhuoma Bianba, Xiaojin Mo, Wei Hu, Zheng Feng, Fangye Zhou and Ting Zhang Tropical Medicine and Infectious Disease 9(8) 175 (2024) https://doi.org/10.3390/tropicalmed9080175
Echinococcus multilocularis delta/notch signalling components are expressed in post-mitotic cells
Genome-wide transcriptome analysis of Echinococcus multilocularis larvae and germinative cell cultures reveals genes involved in parasite stem cell function
Michaela Herz, Magdalena Zarowiecki, Leonie Wessels, Katharina Pätzel, Ruth Herrmann, Christiane Braun, Nancy Holroyd, Thomas Huckvale, Monika Bergmann, Markus Spiliotis, Uriel Koziol, Matthew Berriman and Klaus Brehm Frontiers in Cellular and Infection Microbiology 14 (2024) https://doi.org/10.3389/fcimb.2024.1335946
Treatment of uncomplicated hepatic cystic echinococcosis (hydatid disease)
Effect of Hydroxyurea on Morphology, Proliferation, and Protein Expression on Taenia crassiceps WFU Strain
Diana G. Rios-Valencia, Karel Estrada, Arturo Calderón-Gallegos, Rocío Tirado-Mendoza, Raúl J. Bobes, Juan P. Laclette and Margarita Cabrera-Bravo International Journal of Molecular Sciences 25(11) 6061 (2024) https://doi.org/10.3390/ijms25116061
Britta Lundström-Stadelmann, Matías Preza, Marc Kaethner and Andrew Hemphill 19 219 (2024) https://doi.org/10.1007/978-3-031-54479-8_13
Watch-and-wait approach for inactive echinococcal cysts: scoping review update since the issue of the WHO-IWGE Expert Consensus and current perspectives
Establishment of a secondary infection laboratory model of Echinococcus shiquicus metacestode using BALB/c mice and Mongolian jirds (Meriones unguiculatus)
Yantao Wu, Li Li, Fuling Xu, Hongbin Yan, John Asekhaen Ohiolei, Nigus Abebe Shumuye, Xiaofeng Nian, Wenhui Li, Nianzhang Zhang, Baoquan Fu and Wanzhong Jia Parasitology 1 (2023) https://doi.org/10.1017/S0031182023000604
In Vitro Activities of Dithiocarbamate Derivatives against Echinococcus multilocularis Metacestode Vesicles
Marc Kaethner, Georg Rennar, Tom Gallinger, Tobias Kämpfer, Andrew Hemphill, Patrick Mäder, Ana Luque-Gómez, Martin Schlitzer and Britta Lundström-Stadelmann Tropical Medicine and Infectious Disease 8(12) 517 (2023) https://doi.org/10.3390/tropicalmed8120517
Establishment and application of unbiased in vitro drug screening assays for the identification of compounds against Echinococcus granulosus sensu stricto
Marc Kaethner, Matías Preza, Tobias Kaempfer, Pascal Zumstein, Claudia Tamponi, Antonio Varcasia, Andrew Hemphill, Klaus Brehm, Britta Lundström-Stadelmann and Cristian A. Alvarez Rojas PLOS Neglected Tropical Diseases 17(8) e0011343 (2023) https://doi.org/10.1371/journal.pntd.0011343
Targeting Echinococcus multilocularis PIM kinase for improving anti-parasitic chemotherapy
Transcriptional effects of electroporation on Echinococcus multilocularis primary cell culture
Matías Gastón Pérez, Natalia Rego, Markus Spiliotis, Klaus Brehm and Mara Cecilia Rosenzvit Parasitology Research 121(4) 1155 (2022) https://doi.org/10.1007/s00436-022-07427-5
The combination of carvacrol and albendazole enhanced the efficacy of monotherapy in experimental alveolar echinococcosis
Lurdes Milagros Lopez, Patricia Eugenia Pensel, Julia Fabbri, Clara María Albani, Natalia Elissondo, Guillermo Gambino and María Celina Elissondo Acta Tropica 225 106198 (2022) https://doi.org/10.1016/j.actatropica.2021.106198
Cellular and molecular basis associated with metacestode proliferation in subarachnoid neurocysticercosis
PET/CT helps to determine treatment duration in patients with resected as well as inoperable alveolar echinococcosis
Lars Husmann, Urs J. Muehlematter, Felix Grimm, Bruno Ledergerber, Michael Messerli, Ken Kudura, Hannes Gruenig, Beat Muellhaupt, Barbara Hasse and Martin W. Huellner Parasitology International 83 102356 (2021) https://doi.org/10.1016/j.parint.2021.102356
Echinococcus granulosus sensu lato and Echinococcus multilocularis: A review
Metformin Suppresses Development of the Echinococcus multilocularis Larval Stage by Targeting the TOR Pathway
Julia A. Loos, Valeria A. Dávila, Klaus Brehm and Andrea C. Cumino Antimicrobial Agents and Chemotherapy 64(9) (2020) https://doi.org/10.1128/AAC.01808-19
Drug repurposing applied: Activity of the anti-malarial mefloquine against Echinococcus multilocularis
Britta Lundström-Stadelmann, Reto Rufener and Andrew Hemphill International Journal for Parasitology: Drugs and Drug Resistance 13 121 (2020) https://doi.org/10.1016/j.ijpddr.2020.06.002
A case for adoption of continuous albendazole treatment regimen for human echinococcal infections
EGF-mediated EGFR/ERK signaling pathway promotes germinative cell proliferation in Echinococcus multilocularis that contributes to larval growth and development
Oral treatments of Echinococcus multilocularis-infected mice with the antimalarial drug mefloquine that potentially interacts with parasite ferritin and cystatin