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Mechanisms by which Factor H protects Trypanosoma cruzi from the alternative pathway of complement
Smrithi S. Menon, Galia Ramirez-Toloza, Keith L. Wycoff, Sean Ehinger, Jutamas Shaughnessy, Sanjay Ram and Viviana P. Ferreira Frontiers in Immunology 15 (2024) https://doi.org/10.3389/fimmu.2024.1152000
Trypanosoma cruzi infection induces DNA double-strand breaks and activates DNA damage response pathway in host epithelial cells
Raul Alexander Gonzáles-Córdova, Thamires Rossi dos Santos, Camila Gachet-Castro, Johnathan Andrade Vieira, Lays Adrianne Mendonça Trajano-Silva, Elza Tiemi Sakamoto-Hojo and Munira Muhammad Abdel Baqui Scientific Reports 14(1) (2024) https://doi.org/10.1038/s41598-024-53589-w
Antifungal and Antiparasitic Activities of Metallocene-Containing Fluconazole Derivatives
Yan Lin, Gonzalo Scalese, Christina A. Bulman, Robin Vinck, Olivier Blacque, Margot Paulino, Andres Ballesteros-Casallas, Leticia Pérez Díaz, Gustavo Salinas, Makedonka Mitreva, Tobias Weil, Kevin Cariou, Judy A. Sakanari, Dinorah Gambino and Gilles Gasser ACS Infectious Diseases 10(3) 938 (2024) https://doi.org/10.1021/acsinfecdis.3c00577
Monocyte‐derived extracellular vesicles, stimulated by Trypanosoma cruzi, enhance cellular invasion in vitro via activated TGF‐β1
Ephraim A. Ansa‐Addo, Paras Pathak, Maria V. McCrossan, Izadora Volpato Rossi, Mahamed Abdullahi, Dan Stratton, Sigrun Lange, Marcel I. Ramirez and Jameel M. Inal Journal of Extracellular Vesicles 13(11) (2024) https://doi.org/10.1002/jev2.70014
Trypanosoma cruzi-specific CD8+ T cells and other immunological hallmarks in chronic Chagas cardiomyopathy: Two decades of research
Concepción J. Puerta, Adriana Cuellar, Paola Lasso, Jose Mateus and John M. Gonzalez Frontiers in Cellular and Infection Microbiology 12 (2023) https://doi.org/10.3389/fcimb.2022.1075717
Host Cell Rap1b mediates cAMP-dependent invasion by Trypanosoma cruzi
Copper(I)‐Thiosemicarbazone Complexes with Dual Anticancer and Antiparasitic Activity
João Franco Machado, Fernanda Marques, Teresa Pinheiro, Maria J. Villa de Brito, Gonzalo Scalese, Leticia Pérez‐Díaz, Lucía Otero, João P. M. António, Dinorah Gambino and Tânia S. Morais ChemMedChem 18(14) (2023) https://doi.org/10.1002/cmdc.202300074
Multifunctional organometallic compounds for the treatment of Chagas disease: Re(i) tricarbonyl compounds with two different bioactive ligands
Different Transcriptomic Response to T. cruzi Infection in hiPSC-Derived Cardiomyocytes From Chagas Disease Patients With and Without Chronic Cardiomyopathy
Theo G. M. Oliveira, Gabriela Venturini, Juliana M. Alvim, et al. Frontiers in Cellular and Infection Microbiology 12 (2022) https://doi.org/10.3389/fcimb.2022.904747
Melittin as a promising anti-protozoan peptide: current knowledge and future prospects
Anti-Trypanosoma cruzi Activity and Molecular Docking Studies of 1Hpyrazolo[ 3, 4-b]pyridine Derivatives
Camilo Henrique da Silva Lima, Júlio César de Araujo Vanelis Soares, Joana Lucius de Sousa Ribeiro, et al. Letters in Drug Design & Discovery 17(2) 184 (2020) https://doi.org/10.2174/1570180816666190305141733
Lectin in Host Defense Against Microbial Infections
Fang-Yen Li, Sheng-Fan Wang, Emerson S. Bernardes and Fu-Tong Liu Advances in Experimental Medicine and Biology, Lectin in Host Defense Against Microbial Infections 1204 141 (2020) https://doi.org/10.1007/978-981-15-1580-4_6
PARP Inhibitor Olaparib Causes No Potentiation of the Bleomycin Effect in VERO Cells, Even in the Presence of Pooled ATM, DNA-PK, and LigIV Inhibitors
Valentina Perini, Michelle Schacke, Pablo Liddle, Salomé Vilchez-Larrea, Deborah J. Keszenman and Laura Lafon-Hughes International Journal of Molecular Sciences 21(21) 8288 (2020) https://doi.org/10.3390/ijms21218288
In vitro models for investigation of the host-parasite interface - possible applications in acute Chagas disease
Measuring mitochondrial respiration in adherent cells infected with Trypanosoma cruzi Chagas, 1909 using Seahorse extracellular flux analyser
Laura Maria Gonzalez-Ortiz, Juana Patricia Sanchez-Villamil, Mike A. Celis-Rodriguez, et al. Folia Parasitologica 66 (2019) https://doi.org/10.14411/fp.2019.016
Drug Discovery for Chagas Disease: Impact of Different Host Cell Lines on Assay Performance and Hit Compound Selection
Caio Haddad Franco, Laura Maria Alcântara, Eric Chatelain, Lucio Freitas-Junior and Carolina Borsoi Moraes Tropical Medicine and Infectious Disease 4(2) 82 (2019) https://doi.org/10.3390/tropicalmed4020082
Phenotypic screening approaches for Chagas disease drug discovery
Chagas Disease - Basic Investigations and Challenges
Rosa Lidia Solís-Oviedo, Víctor Monteon, Ruth López and Ángel de la Cruz Pech-Canul Chagas Disease - Basic Investigations and Challenges (2018) https://doi.org/10.5772/intechopen.77236
The marsupial trypanosome Trypanosoma copemani is not an obligate intracellular parasite, although it adversely affects cell health
Host triacylglycerols shape the lipidome of intracellular trypanosomes and modulate their growth
Felipe Gazos-Lopes, Jessica L. Martin, Peter C. Dumoulin, Barbara A. Burleigh and Isabelle Coppens PLOS Pathogens 13(12) e1006800 (2017) https://doi.org/10.1371/journal.ppat.1006800
Modern Proteomics – Sample Preparation, Analysis and Practical Applications
John E. Wiktorowicz and Kizhake V. Soman Advances in Experimental Medicine and Biology, Modern Proteomics – Sample Preparation, Analysis and Practical Applications 919 443 (2016) https://doi.org/10.1007/978-3-319-41448-5_21